Canine Postpartum Diseases Flashcards
Metritis:
Definition?
Inflammation of the uterus (endometrium and myometrium)
Metritis:
A (local/systemic) infection?
systemic - fever, depression, purulent vulvar discharge
Metritis:
Diagnosis via: 1. 2. 3. 4.
- CBC
- Vaginal cytology
- Culture
- U/S
Metritis:
Treatment?
PGF2a to evacuate the uterus. Can use oxytocin, but it’s less effective.
Pyometra:
Occurs during what phase of estrous cycle?
Diestral - during progesterone phase.
Pyometra:
Seen during what days post-estrus in:
- bitch?
- queen?
- 60-90 days
2. anytime
Pyometra:
More common in (younger/older)?
older individuals
Pyometra:
May be associated with what other disease?
Cystic endometrial hyperplasia
Cystic Endometrial Hyperplasia - Metritis Pyometra complex (CEHMP)
Definition?
Acute or chronic post-estrual disease with variable clinical signs/pathologic findings
Cystic Endometrial Hyperplasia - Metritis Pyometra complex (CEHMP)
Incidence (decreases/increases) with age?
increases
Cystic Endometrial Hyperplasia - Metritis Pyometra complex (CEHMP)
Pathogenesis:
Normal down-regulation of estrogen receptors due to increases P4 may be defective. Results in dogs getting prolonged effects of E2 on endometrium, leading to increases in P4 receptors.
Most common organism to cause secondary bacterial invasion?
E.Coli
What effect does increasing P4 have on estrogen-receptors?
down regulates them
Open vs Closed Pyometra:
Which one presents as more systemically ill?
Which one has discharge from vuvla?
Closed.
Open
Main clinical sign of open pyometra?
copious red-brown to yellow-green foul smelling vulvar discharge
Best ways to diagnose pyometra:
1.
2.
3.
- abdominal palpation
- radiography
- U/S
What will you see on a radiograph of pyometra?
outline of pus-filled uterine horns
Treatment of choice for pyometra?
OHE
Medical Therapy for Pyometra:
1, What do you give?
- Effect?
- For open or closed pyometra only?
- PGF2a - Lutalyse or Estrumate.
- smooth muscle contractions for uterine evacuation.
- open cervix pyometra only
Describe the technique for PGF2a administration as medical treatment of open pyometra
.05 mg/kg TID of lutalyse,
.01 mg/kg QUD misoprotol
100 micrograms per os every other day to help dilate cervix or place topically on cervix
Medical Therapy of Pyometra: Considerations:
1.
2.
3. Recommendation?
- Culture/sensitivity for appropriate microbial therapy
- Side effects of PGF2a including panting, salivating, vomiting, defecation, vocalization
- breed next occurring estrus, than spay.
For brood bitches:
- Breed (early/late).
- Try not to…
- Spay when?
- starting early.
- miss a cycle
- when you have obtained all litters desired to reduce risk of CEH/pyometra