BIOL 220: Ch. 10 Flashcards
Terms and concepts from Ch. 10: Muscles
three types of muscles in the body
skeletal, cardiac, smooth
there are over ____ skeletal muscles and together they form the _____
700; muscular system
properties of muscle tissue (4)
excitability
contractility
elasticity
extensibility
excitability
muscle cells are responsive to input from stimuli
contractility
stimulation of muscle fiber can lead to contraction and shortening of the muscle fiber
elasticity
contracted muscle cell can return to resting length when applied tension is removed
extensibility
ability of a muscle fiber to be stretched beyond its resting length
each skeletal muscle is considered an organ because it contains…
all four tissue types
skeletal muscle is ____ in appearance, _____ in movement, and usually attached to ____
striated; voluntary; bones
functions of skeletal muscle tissue (5)
body movement maintenance of posture temperature regulation storage and movement of materials support
fascicles
bundles in which muscle fibers are organized to comprise each muscle; covered by perimysium
muscle fibers contain…
myofibrils
myofibrils are composed of…
myofilaments
each muscle has ____ layers of concentric ____ ____ composed of ____ and _____ fibers
three; connective tissue; collagen; elastic
CT provides ____, _____, and _____.
protection, sites for blood vessel and nerve distribution, a means of attaching the muscle to the skeleton
CT components of skeletal muscle from outer to inner (5)
superficial fascia deep fascia epimysium perimysium endomysium
superficial facia
dense irregular connective tissue comprising the epimysium; separates muscle from skin
deep fascia
dense irregular connective tissue comprising the epimysium; surrounds each muscle and separates muscles from each other
epimysium
surrounds the entire muscle
perimysium
dense irregular connective tissue surrounding the fascicles
endomysium
areolar connective tissue comprising the innermost layer that surrounds and electrically insulates each muscle fiber
muscle
multiple fascicles housing many many muscle fibers, connective tissue coverings, blood vessels, nerve fibers
muscle fibers
elongated, multinucleated cylindrical fiber (cell); contains myofibrils, separated from other fibers by delicate layer of areolar connective tissue (endomysium); exhibits striations
myofibrils
long, cylindrical contractile element within muscle fiber; composed of myofilamants; exhibits striations
myofibrils are as long as the ____ _____ itself
muscle fiber
myofilaments
short, contractile proteins of two types: thick (myosin) and thin (actin, tropomyosin, and troponin)
at the ends of each muscle, all of the CT merge to form a _____
tendon
tendon attaches muscle to..
bone, skin, or another muscle
tendons are usually cordlike in appearance, but some appear as a flat sheet, termed an _____
aponeurosis
Upon conraction of a muscle, one of the articulating bones _____ and the other one does not
moves
origin
less moveable point of attachment
insertion
more moveable point of attachment
sarcolemma
plasma membrane of skeletal muscle fiber
sarcoplasm
cytoplasm of a skeletal muscle fiber
sarcoplasmic reticulum
smooth ER of skeletal muscle fiber
two main structure unique to skeletal muscle
transverse tubules (T-tubules terminal cisternae
transverse tubulues
deep invaginations of the sarcolemma that extend into the sarcoplasm; orms a network of tubules that enables muscle impulses to spread quickly internally
terminal cisternae
blind sacs of the sarcoplasmic reticulum
triad
two terminal cisternae + T-tubule
myofibrils have the ability to ____, resulting in the contraction of the _____
shorten; muscle fiber
myofilaments do not run the entire length of the muscle fiber, but they are organized into…
repetitive groupings
two type of myofilaments
thick (myosin)
thin (actin)
thick filaments diameter
11 nm (twice thin)
thick filaments are composed of bundled molecules of…
myosin
myosin has a _____ and elongated ___
head;tail
the heads of myosin form ______ with the thin filaments during contraction
crossbridges
thin filaments diameter
5-6 nm
thin filaments are comprised of two strands called _____ and ____ twisted around each other
F-actin
G-actin
F-actin is…
filamentous
G-actin is..
globular
regulatory proteins of thin filament (2)
tropomyosin
troponin
muscle function
metabolic activities; contraction
sarcolemma function
surround muscle fiber and regulates entry and exit of materials
sarcoplasm function
site of metabolic processes for normal muscle fiber activities
sarcoplasmic reticulum function
stores calcium ions needed for muscle contraction
terminal cisterna function
site of calcium ion release to promote muscle contraction
transverse tubule function
quickly transports impulse from the sarcolemma throughout the entire muscle fiber
thick filament function
bind to thin filament and cause contraction
thin filament function
thick filaments bind and cause contraction
actin and function
double-stranded contractile protein; binding site for myosin to shorten a sarcomere
tropomyosin and function
double-stranded regulatory protein; covers the active sites on actin, preventing myosin from binding to actin when muscle fiber is at rest
troponin and function
regulatory protein that holds tropomyosin in place and anchors to actin; when calcium ions bind to one of its subunits, troponin changes shape, causing the tropomyosin to move off the actin active site, and this permits myosin binding to actin
connectin and function
single molecular filament of a giant protein; plays role in organization of the sarcomere and helps provide passive tension within sarcomere
nebulin and function
filament of giant protein; possibly to regulate the length of the thin filament
what causes the striated appearance of skeletal muscle?
think and thick filaments
dark bands are called ____
A bands
A bands contain..
the entire myosin molecule and an overlapping portion of actin
light bands are called ____
I bands
I bands contain…
thin filaments, but no thick filaments
I bands also contain the protein ____
titin
H zone (H band)
light, central region of the A band where there are no thin filaments
M line
protein meshwork in the H zone that keeps the thick filaments aligned
Z disc (Z band)
protein structure in the middle of the I band that serves as the attachment site for one end of the thin filament
sarcomere
functional contractile unit in a skeletal muscle fiber; are between two adjacent Z discs
myofibrils contain multiple and repeating..
sarcomeres
each sarcomere ___ as the muscle fiber contracts
contracts
does the sarcomere shorten when the muscle contracts?
yes
does the A band shorten when the muscles contracts?
no
does the h zone shorten when the muscle contracts?
yes
does the m line shorten when the muscle contracts?
no
does the I band shorten when the muscle contracts?
yes
does the z disc shorten when the muscle contracts?
no
muscle fibers shorten by the interaction between thin and thick filaments within each sarcomere, generating..
tension
mechanism for contraction is explained by..
sliding filament theory
what four things occur during contraction according to the sliding filament theory?
- width of A band remains constant, but H zone disappears
- Z discs in each sarcomere move closer together
- sarcomere narrows in length
I bands narrow
_____ of thick and thin filaments never changes, only their _____ changes
length; position
neuromuscular junctions
region where the motor neuron comes in close proximity to the muscle fiber
muscle contractions begins when a ____ impulse stimulates an _____ in muscle fiber
motor neuron; impulse
components of neuromuscular junction (6)
synaptic knob synaptic vesicles motor end plate synaptic cleft Ach receptors acetylcholinesterase (AChE)
synaptic knob
expanded tip of an axon
synaptic vesicles
membrane sacs filled with acetylcholine (ACh)
motor end plate
region of sarcolemma that has folds and indentations to increase the SA covered by the synaptic knob
synaptic cleft
narrow sapce separating the synaptic knob and the motor end plate
ACh receptors
on the motor end plate; bind ACh
acetylcholinesterase (AChE)
enzyme in the synaptic cleft that rapidly breaks down ACh
physiology of muscle contraction (6)
- a nerve impulse causes ACh to be released into the synaptic cleft
2, ACh binds to receptors in the motor end plate intiating a muscle impulse along the sarcolemma and T-tubule membranes - spread of the impulse down T-tubules causes calcium to leak out of terminal cisternae
- calcium ions bind to troponin, causing tropomosyin to uncover active sites on G-actin
- myosin heads bind to actin and form crossbridges
- in the presence of ATP, myosin cycles through attachment, pivot, detach, and return events (ATP also necessary for muscle fiber relaxation)
motor units
consists of a single motor neuron and the muscle fibers it control
a motor unit typically controls only ___ of the muscle fibers in an entire muscle
some
size of the motor unit and degree of control provided are ____ related
inversely
small motor units provide ___ control
precise
all or none principle
obeyed by all muscle fibers, it means that a muscle fiber contracts completely or not at all
when a motor unit is stimulated, all muscle fibers under its control will..
contract
benefit of having a larger motor unit versus smaller motor units?
it saves space in the brain, needing fewer neurons to accomplish the same job
muscle tone
constant tension in a resting muscle
motor units are stimulated ____ to avoid fatigue
randomly
type of muscle contraction (2)
isometric contraction
isotonic contraction
isometric contraction
length is constant; tension is changing
isotonic contraction
tension is constant; length is changing
types of isotonic contraction (2)
concentric contraction
eccentric contraction
concentric contraction
muscle is shortening
eccentric contraction
muscle is lengthening
types of skeletal muscle fibers (3)
- slow oxidative (SO) fibers
- fast oxidative (FO) fibers
- fast glycolytic (FG) fibers
slow oxidative fibers and fast oxidative fibers are ____ processes
aerobic
fast glycolytic fibers are ____ processes
anaerobic
the ratio of fiber types within a muscle determines the ____ and _______ of the contraction
speed, sustainability
SO fiber capacity to make ATP
high, aerobic
FO fiber capacity to make ATP
moderate, aerobic
FG fiber capacity to make ATP
limited, anaerobic
concentration of capillaries in SO fibers, FO fibers, and FG fibers
extensive
moderately extensive
sparse
color of fibers: SO, FO, FG
dark red; lighter ed; white (pale)
amount of myoglobin of fibers: SO, FO, FG
large, medium, small
fiber distribution: SO, FO, FG
SO: muscles of trunk, especially postural muscles (contract almost continually)
FO: greatest abundance in muscles of the lower limbs
FG: greatest abundance in muscles of upper limbs
skeletal muscles usually contain ____ muscle fiber types
all three
a single motor unit controls one muscle fibers of ____ type
the same
there are no ____ muscle fibers in muscles that require swift but brief contractions
slow
patterns of fascicle arrangements (4)
- circular
- parallel
- convergent
- pennate
- unipennate
- bipennate
- multipennate
circular pattern
fibers arranged concentrically around an opening
functions as a sphincter to close a passageway or opening
circular pattern muscle example
oribularis oris (mouth)
parallel pattern
fascicles are parallel to the long axis of the muscle
body of muscle increases in diameter with contraction
high endurance, not very strong
parallel pattern muscle example
rectus abdominus (abs)
convergent pattern
triangular muscle with common attachment site
directions of pull muscle can be changed
does not pull as hard as equal-sized parallel muscle
convergent pattern example
pectoralis major
pennate pattern
muscle body has one or more tendons
fascicles oblique angle to tendon
pulls harder than a parallel muscle of equal size
unipennate and example
all muscle fibers on the same side of the tendon i.e. extensor digitroum
bipennate and example
muscle fibers on both sides of the tendon i.e. rectus femoris
multipennate and example
tendon branches within the muscle i.e. deltoid
muscle atrophy
wasting of tissue that results in reduction of muscle size, tone, and power; can be caused by lack of stimulation
muscle hypertrophy
increase in muscle fiber size (not an increase in number of muscle fibers); results from repetitive stimulation of muscle fibers
during muscle hypertrophy, mitochondria ____ in number, therefore the amount of ATP increase
increase
during muscle hypertrophy, both myofibrils and myofilaments ___ in number, all resulting in the muscle ____ in size
increase, increase
lever
elongated, rigid object that rotate around a fixed point called a fulcrum
fulcrum
fixed point on which a lever rotates around
rotation occurs when an ___ applied to one point of the lever exceeds a ____ located at some other point
effort; resistance
three classes of levers in human body
- first-class lever
- second-class lever
- third-class lever
agonist
produces a specific movement when it contracts; also called prime mover
antagonist
muscle whose action opposes that of an agonist
synergist
muscle that assists the agonist in performing its action
criteria of naming skeletal muscles (6)
- muscle action
- specific body regions
- muscle attachments
- orientation of muscle fibers
- muscle shape and size
- muscle heads/tendons of origin
muscle action (4)
adduction
abductor
flexor
extensor
specific body regions (14)
oris cervicis brachial carpi pollicis gluteal femoris hallucis anterior porterior or dorsal/dorsi superior inferior superficialis profundus
muscle attachments (5)
sternum and clavical between the ribs subscapular fossa fibula zygomatic bone
orientation of muscle fibers (3)
rectus
oblique
orbicularis
muscle shape and size (10)
deltoid quadtratus trapezius longus brevis major minor maximus medius minimus
muscle heads/tendons of origin (3)
biceps
triceps
quadriceps
adductor
adducts body part
abductor
abducts body part
flexor
flexes a joint
extensor
extends a joint
oris
mouth
cervicis
neck
bracial
arm
carpi
wrist
pollicis
thumb
gluetal
buttocks
femoris
thigh
hallucis
great toe
anterior
toward the front of the bod
posterior or dorsal/dorsi
toward the back of the body
superficialis
superficial
profundus
deep
sternum and clavicle
cleido
rectus
straight
oblique
angled
orbicularis
circular
deltoid
traingular
quadratus
rectangular
trapezius
trapezoidal
longus
long
brevis
short
major
larger of two muscle
minor
smaller of two muscles
maximus
largest
medius
medium sized
minimus
smallest
biceps
two heads
triceps
three heads
quadriceps
four heads
cardiac muscle cells are found within the ____ ____
heart wall
qualities of cardiac muscles (6)
striated one or two nuclei form y-shaped branches intercalated discs autorhythmic involuntary
intercalated discs
junctions to which other adjacent cardiac muscle fibers can join and comprise of gap junctions
autorhythmic
able to generate muscle impulse without nervous stimulation
cardiac muscle cells have their nuclei ____ location
centrally
smooth muscle is found in the ____ of viscera and ____
walls; blood vessels
smooth muscle characteristics (5)
short fusiform cells one centrally located nucleus no striations thin filaments attached to dense bodies under involuntary control
what feature is not present in skeletal muscle but present in in smooth muscle?
z-disc
smooth muscle cells allow contractions in ____ directions
all