ANTINEOPLÁSICOS Flashcards

1
Q

FÁRMACOS CITOTÓXICOS QUE TB SON INMUNOSUPRESORES

A

ciclofosfamida
metotrexato

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2
Q

alquilantes

A

ciclofosfamida
melfalán

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3
Q

pseudoalquilantes

A

cisplatino
oxaliplatino

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4
Q

antimetabolitos

A
  1. antag folato
    a. metotrexato
  2. análisis pirimidinas
    a. 5-fluorocacilo
    b. citarabina
  3. análogos purinas
    a. fludarabina
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5
Q

a quien inhibe fludarabina y citarabina

A

ADN polimerasa

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6
Q

a quien inhibe 5-fluororacilo

A

timidilato sintasa

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7
Q

inhibidores topoisomerasa

A
  1. doxorrubicina
  2. mitoxantrona
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8
Q

para qué se usan antiandrógenos

A

cáncer próstata

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9
Q

antiestrógenos uso

A

cáncer mama

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10
Q

inhibidores aromatasa

A

anastrozol
letrozol

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11
Q

uso inhibidores aromatasa

A

cáncer mama postmenopausia

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12
Q

uso gestágenos

A

tumores endometrio para desacelerar el crecimiento de células tumorales

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13
Q

glucocorticoides uso

A

inhibición proliferación linfocitos en linfomas/leucemias, reducir nauseas y vómitos

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14
Q

alcaloides vinca

A

vincristina

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15
Q

taxanos

A

paclitaxel
docitaxel

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16
Q

ac monoclonales

A

trastuzumab: antiher2
cetuximab: antiEGFR
bevalizumab: antiVEGF
Rituximab: antiCD20

17
Q

inhibidores proteín quinasa

A

todo lo que acabe en INIB
imatinib
erlotinib