Allergic reactions

Question 1

4 types ABCD

Answer 1

A= allergic, anaphylaxis, atopy
B=antiBody
C: immune Complex
D=Delayed

Question 2

Type 1

Answer 2

an IgE-mediated reaction, attach to receptors on basophils, mask cells, and eosinophils, resulting in inflammatory mediators and cytokine release

Question 3

Type 2

Answer 3

a cytotoxic reaction, IgM or IgG antibodies bind to surface antigens on normal tissue cells
○ E.g. ABO incompatibility transfusion reaction

Question 4

Type 3

Answer 4

immune-complex reactions result from IgG or IgM antibodies-antigen complexes that accumulate in the tissue and circulation. This reaction also attracts granulocytes
○ E.g. RA

Question 5

Type 4

Answer 5

delayed T cell type reaction (hypersensitivity), mediated by T cells and monocytes/macrophages rather than by antibodies.
○ Contact dermatitis

Question 6

Atopic march

Answer 6

development of one allergic disease predisposes the child to another disorder