Adult - Respiratory II Flashcards
What are the five conditions which may cause significant night sweats?
TB menopause AIDS lymphoma endocarditis
What are the signs and symptoms of TB?
majority of people are ASYMPTOMATIC if present: weight loss night sweats low grade fever cough
What is the typical cough progression in TB?
dry cough progressing to productive and sometimes blood tinged
What are the two tests definitively diagnostic for TB?
culture
CXR - small, homogenous infiltrate in upper lobes
Is TB reportable?
yes
What is INH?
the abbreviation for isoniazid
What is the medication regimen for TB?
RIPE R - Rifampin I - Isoniazid (INH) P - Pyrazinamide E - Ethambutol
When can the 4th drug in the TB regimen be dropped?
if the isolate is fully suceptible to RIF and INH
How long are the drugs given in TB?
INH and RIF for at least 6 months
pyrazinamide for 2 months
How is TB therapy monitored?
Weekly sputum smears and cultures for the first 6 weeks
Then monthly until negative cultures documented
Continued positive TB cultures after what time frame would raise the suspicion of drug resistance?
3 months
What baseline studies should be obtained prior to starting TB drug therapy?
LFTs
CBC
serum creatinine
What lab work must be monitored weekly while on INH?
LFTs
What needs to be monitored in people taking ETHAMBUTOL?
visual acuity
red-green color perception
PPD reading of 5 mm considered positive in what populations?
HIV patients
contacts of a known cause
those with typical TB presentation on CXR