4.1 Structure and Replication of the Genetic Material Flashcards
Define gene
units of inherited information that carry a code for specific traits or functions
3 main components of a DNA molecule
ring-shaped sugar(deoxyribose), phosphate group, nitrogenous base pairs
Another word for DNA sequence
codon
What does DNA stand for
Deoxyribonucleic acid
4 types of nitrogenous bases found in DNA
Guanine, cytosine, adenine, thymine
What form does a cell’s DNA take in the interphase stage
chromatin
Summarize what happens during the process of cell division in mitosis
- M phase
Mitosis: nucleus + duplicated chromosomes distributed into 2 daughter nuclei
Cytokinesis: cleavage furrow + cell plate, cytoplasm divides+ cell splits into 2 genetically identical daughter cells
Describe how a cell’s chromatin changes as the cell prepares to divide.
Interphase: chromatin
Early mitosis: chromosomes (chromatin compacted)
Late mitosis: sister chromatids (chromosome duplicated)
What is the role of interphase?
Preparing for cell division
-doubling organelles + DNA
-checks codons + base pairs (both DNA) for errors
List each phase in the cell cycle.
G1, S, G2, M(mitosis and cytokinesis)
G1 phase
-doubles organelles
-carries out metabolic processes + reg. cell activities
S phase
DNA is doubled
G2 phase
DNA(codons+base pairs) checked for errors
Explain why DNA’s structure is called the double helix.
-made of 2 long strands of DNA that are intertwined + look like a twisted ladder
List 2 human traits
Any trait…
E.g curly hair, brown eyes, straight hair
Give 3 reasons why cells divide
- Growth
- Repair
- Reproduction
How are the following terms related: DNA, chromatin, chromatid and chromosome?
-They are all different names for DNA based on how it’s packaged
-Chromatin: long, loose fibres of DNA
-Chromosome: tightly wrapped fibres of DNA
-Chromatid: duplicates to form chromosomes (for cell
division
What is the role of DNA in a cell that’s not dividing?
Interphase: DNA exists as a mass of very long fibres —->chromatin
Template strand: AGTCCG. What is the complementary strand?
TCAGGC
What is the codon in AGTCCG
AGT
Why is it necessary for a cell to replicate its DNA prior to cell division?
So that daughter cells can have a complete set of genetics/DNA
Histone vs. Nucleosome
histone proteins: proteins that help in the packaging of DNA structures
nucleosomes: basic unit of DNA packaging (8 histone proteins with DNA wrapped around it)
How many ways can the nucleotide sequence GAT be arranged?
6
What are telomeres, and how do they protect genetic information?
protective caps on the ends of chromosomes that prevent them from losing DNA
What happens when telomeres get too short?
Cells can’t divide and can cause death
What can telomeres be an indicator of?
Age and general health
How many chromosomes does a human body cell contain in the G1 phase, just before M phase and just after cytokinesis?
46
Suggest what would happen to a single-celled organism if it were to go through many rounds of mitosis but not cytokinesis.
cell keeps dividing and doubling organelles + chromosomes + nuclei = cell will explode
Suggest reasons why blood cells and skin cells reproduce more often than other cells in the body.
-constantly being lost (neurons+muscle cell rarely need to be replaced but skin cells wear out fast)
-RBCs: constantly bursting and need to be replaced (short lifespan)
-WBCs: don’t live longer than 20 day
What are pyrimidines and give two examples
single-ring structures (thymine+cytosine)
What are purines and give two examples
double-ring structures (adenine+guanine)
What is the name of the bond that links the sugar of one nucleotide to the phosphate group of the next
Phosphodiester bond
M phase meaning
Mitotic phase
Give an example of a monomer
Nucleotide because it makes up the polymer
Give an example of a polymer
DNA because it’s made up of monomers
genetics
Genetics is the study of genes, heredity, and the variation of organisms
true or false: the DNA in prokaryotes is packaged
false
trait
a characteristic of an organism (e.g. curly hair)
acquired trait
traits we acquire as we live
(e.g. knowledge)