4. Anemia: Diagnosis and Clinical Considerations

Question 1

1. Which of the following laboratory results would not be a usual criterion for making a diagnosis of anemia?
   a.Decreased hemoglobin level
   b.Decreased hematocrit level
   c.Decreased platelet count
   d.Decreased RBC count

Answer 1

c.Decreased platelet count

Question 2

2.What condition is not a cause of anemia?
a. Dietary deficiency
b.Moderate exercise
c. Decreased RBC production
d.Increased RBC destruction or loss

Answer 2

b.Moderate exercise

Question 3

3.Which response represents the most complete and correct listing of the most common clinical signs of anemia?
a.Fatigue,weakness,dyspnea, pallor
b. Urticaria, hypertension, inflammation, nausea
c. Nausea,hypertension, temperature elevation, melena
d. Rapid pulse, inflammation, temperature elevation,dehydration

Answer 3

a.Fatigue,weakness,dyspnea, pallor

Question 4

4. What is the most commonly accepted method for measuring hemoglobin?

a. Conversion of hemoglobin to oxyhemoglobin,followed by spectrophotometric measurement
b.Iron content measured by radioimmunoassay technique
c. Copper sulfate measured by specific gravity
d. Conversion of hemoglobin to cyanmethemoglobin,followed by spectrophotometric measurement

Answer 4

d. Conversion of hemoglobin to cyanmethemoglobin,followed by spectrophotometric measurement

Question 5

5.How is hematocrit measured on automated hematology instruments?
a.Centrifugation
b. Photometrically
c. Calculation (MCVxRBC count)
d. Calculation(MCHx Hgb)

Answer 5

c. Calculation (MCVxRBC count)

Question 6

6. A patient has the following results: Hct 26%; Hgb 8g/dL; and RBC count 3.5 x 10%/μL.Calculate the RBC indices-MCV,MCH,and MCHC-and determine the classification of the anemia.
   a. MCV 88 fL; MCH 30 pg; MCHC 33 g/dL; normocytic,normochromic
   b. MCV 101 fL; MCH 33 pg; MCHC 35 g/dL;macrocytic,normochromic
   c. MCV 74 fL; MCH 22 pg; MCHC 31 g/dL; microcytic,hypochromic
   d. MCV 70 fL; MCH 22 pg; MCHC 38 g/dL; microcytic,hyperchromic

Answer 6

c. MCV 74 fL; MCH 22 pg; MCHC 31 g/dL; microcytic,hypochromic

Question 7

7. Which of the following would not be characteristically found on a peripheral blood smear in a case of anemia?
   a. Anisocytosis and/or poikilocytosis
   penheimer bodies
   c. Cabot rings and Heinz bodies
   d. Döhle bodies and toxic granules

Answer 7

d. Döhle bodies and toxic granules

Question 8

8. What is the diagnostic value of the reticulocyte count in the evaluation of anemia?
   a. Determines response and potential of the bone marrow
   b.Determines compensation mechanisms for anemia
   c.Determines the corrected RBC count after calculation
   d.Determines the potential sampling error for RBC count

Answer 8

a. Determines response and potential of the bone marrow

Question 9

9.Which of the following is a lesser factor to be considered in the interpretation of a bone marrow aspirate smear?
a. Maturation of red and white blood cell series
b.M:E ratio
c. Type and amount of hemoglobin
d.Estimate of bone marrow activity

Answer 9

c. Type and amount of hemoglobin