22. Mutiple Myeloma and Related Plasma Cell Disoders

Question 1

1.Which laboratory test(s) provide the most important prog-nostic information in multiple myeloma?
a.Hemoglobin
b.Albumin
c.β2-microglobulin
d. All of the above

Answer 1

d. All of the above

Question 2

2. Which list would contain diagnostic criteria for multiple myeloma?
   a. Biopsy-proven plasmacytoma and 10% to 30% plasma cells
   b. More than 30% plasma cells in bone marrow
   c. Biopsy-proven plasmacytoma and M-spike present See answers at the back of this book.
   d. Monoclonal protein and M-spike present

Answer 2

a. Biopsy-proven plasmacytoma and 10% to 30% plasma cells

Question 3

3. Which of the following would be diagnostic criteria for waldenstrom’s macroglobulinemia ?

a. IgM M-spike and hyperviscosity
b. Lytic bone lesions and rouleaux
c.Renal failure and more than 30% plasma cells
d.M-spike of IgM,IgG, or IgA; low-normal levels of other immunoglobulins; inabilityto make light chains

Answer 3

b. Lytic bone lesions and rouleaux

Question 4

4. What does staging refer to ?

a. Bone marrow compatibility
b. Estimate of disease severity
c.Chemotherapy regimen
d. Determination of specific immunoglobulin in heavy-chain disease

Answer 4

c.Chemotherapy regimen