4/5 Flashcards
immune effects of glucocorticoids
- block phospholipase A2
- block NFkB
- decreases T and B cells (T is most important)
- blacks neutrophil adhesion (increases counts)
rhus dermatitis
same as poison ivy
degrees of burns
- first = only epidermis, no blistering, red
- second = into dermis, blistering
- third = full dermis, white, no pain
pyloric stenosis vs immature LES
pyloric stenosis = olive shaped mass and projectile vomiting
LES = no findings on exam, small volume vomiting
- both common causes of newborn vomiting
closure of neural tube
by week 4
- most teratogens cause damage in weeks 3-8
trypanosoma brucei
African sleeping sickness
trypanosoma cruzi
Chagas disease, in South/Central America
cold induced duiresis
cold causes blood to leave periphery and enter circulation
- high ANP, low ADH leads to diuresis
squamous cell carcinoma in situ
actinic keratosis
side of MLF
ride MLF controls right adduction and left MLF controls left adduction
warfarin factors
2, 7, 9, 10 protein C and S
first factor to be decreased after warfarin
7
mechanism of menopause
- age related decrease in follicles
- lower estrogen production which is normal produced by granulosa cells in follicles
- very high FSH, high LH, low estrogen
- causes hot flashes, etc
blood gas in COPD
high CO2, low O2, high bicarb for respiratory acidosis compensation
RBC disorder where treatment is splenectomy
spherocytosis
seteroline
SSRI
treatment for ethylene glycol poisoning
fomepizole
order of puberty in girls
boobs, pubes and menarche
epimere and hypomere
epimere = erector spinae and intervertebral muscles hypomere = everything else
HTLV
causes T cell leukemia and lymphoma (mycosis fungoides)
transcobalamin
R factor - binds B12
- produced in salivary glands
complication of levothyroxine
atrial fibrillation due to increased beta activation
acetyl CoA carboxylase
first step in FA synthesis, conversion of acetyl CoA to malonyl CoA
deficient enzyme in Fabry’s
galactosidase
major complication in Fabry’s
progressive renal failure, CV disease
treatment for homocysteinuria
B6 (cofactor)
PCP MOA
NMDA antagonist
pupil in CNIII injury
damage to parasympathetics, dilated pupil
ovarian tumor resembling glomerulus
yolk sac tumor
causes of sensorineural hearing loss
- Meniere’s disease
- acoustic neuroma
- longstanding noise exposure
- otitis interna
cocaine can cause (heart)
coronary vasospasm
irregular bleeding and thyroid
hypothyroidism, can also cause constipation
caffeine MOA
antagonism of adenosine in CNS
drug for aplastic anemia
methimazole
carvedilol
is a beta blocker with some alpha effects
retinitis pigmentosum
- inherited
- rods affected leading night blindness
- bone spicule shapes
- starts in periphery
Kluver Bucy syndrome
amygdala lesion
breathlessness in pregnancy
increase in minute ventilation due to increase in tidal volume
coughing with vomiting
pertussis
diagnosis of h pylori
scope or urease breath test
cystic hygroma
Turner syndrome
drugs to treat brain tumors
nitrosureas
demeclocycline
ADH antagonist
hypocalcemia in blood transfusions
due to citrate chelation
breast cancer treatment in patient with history of endometrial cancer
aromatase inhibitor = anastrozole
treatment of viral pericarditis
NSAID
resistance in strep pneumo
alteration of PBP