3/30 Flashcards
blood pressure med causing peripheral edema
CCB (only one that is not a diuretic)
IbK kinase
activated during TLR binding, leading to ubiquitination of IkB, release of NFkB, leading to activation of immune cell
prolactin is activated by…
TRH and VIP (can occur in autoimmune thyroiditis
levels increased in menopause
FSH
more severe illness in Dengue is related to…
infection with different serotype
most important part of diptheria treatment
antitoxin (then antibiotics and vaccine)
mutations in hypertrophic cardiomyopathy
sarcomere proteins (beta-myosin heavy chain and myosin binding protein G)
mutation in muscular dystrophy
dystrophin
doxorubicin causes
dilated cardiomyopathy
submucosal gland in GI tract
in esophagus and duodenum
differential in dexamethasone suppression
ACTH can’t be suppressed = ectopic source
- can be suppressed = pituitary adenoma
age related eye changes
myopia can be improved because of worsening presbyopia (patient can think diet led to an improvement)
part of the heart most anterior
right ventricle (left sternal border in fourth intercostal space)
stages of lobar pneumonia
- congestion
- red hepatization
- gray hepatization
- resolution
antibiotic with increase in CK and myopathy
daptomycin
MOA of daptomycin
similar to vanco, creates membrane channels in cell wall
vitamin deficiency similar to B12
vitamin E (also folate)
type of gene VHL
ubiquitin ligase
type of gene BRCA
DNA repair
blood pressure med causing pulmonary edema
mannitol (used with caution in patients with heart failure and pulmonary edema)
somatic symptom disorder
anxiety or preoccupation with one symptom
red pulp in spleen
removal of defective RBCs
cord factor
in TB, leads to high virulence and serpentine growth
hydroxylation of vitamin D
25 in the liver, 1 in the kidney
treatment of ophthalmopathy in graves
corticosteroids
systemic infection with cryptococcus =
meningoencephalitis
late complication of Fabry’s
renal disease
warfarin induced skin necrosis
due to protein C or S deficiency (leads to prothrombotic state)
most specific for RA
anti-CCP
CFTR transporter in CF lungs
secretes Cl-, inhibiting sodium reabsorption by ENaC and keeping water in the lumen
- in CF, Cl- cant be secreted, so more sodium is reabsorbed and more water comes in leading to dehydrated mucus
nerve that can be stimulated in obstructive sleep apnea
glossopharyngeal nerve
antibodies in CREST
anti centromere
pathway affected in fatty alcoholic steatosis
fatty acid oxidation leads to a build up of fat in liver
thing associated with poorly differentiated, aggressive breast tumors
increased expression of HER2/Neu (tyrosine kinase)
treatment for TCA overdose
sodium bicarb
mechanism for sequelae of endocarditis
septic embolization
fluctuating lymphadenopathy
follicular lymphoma
DRESS lab increase
eosinophils and ALT
causes of DRESS
anticonvulsants, allopurinol, sulfonamides, and antibiotics
neurotransmitter decreased in Huntingtons
GABA
endo vs exo nuclease
endo = in middle of molecule exo = front end of molecule
measles can make what vitamin deficiency worse
vitamin A
S3 is best heard….
at the end of expiration (heart is closest to chest wall)
SA node is located
in the right atrium near the opening of the SVC
encephalitis associated with flaccid paralysis
west nile
CD31
PECAM, seen in angiosarcoma of liver
