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AAA - Board by day > 3/30 > Flashcards

3/30 Flashcards

1
Q

blood pressure med causing peripheral edema

A

CCB (only one that is not a diuretic)

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2
Q

IbK kinase

A

activated during TLR binding, leading to ubiquitination of IkB, release of NFkB, leading to activation of immune cell

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3
Q

prolactin is activated by…

A

TRH and VIP (can occur in autoimmune thyroiditis

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4
Q

levels increased in menopause

A

FSH

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5
Q

more severe illness in Dengue is related to…

A

infection with different serotype

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6
Q

most important part of diptheria treatment

A

antitoxin (then antibiotics and vaccine)

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7
Q

mutations in hypertrophic cardiomyopathy

A

sarcomere proteins (beta-myosin heavy chain and myosin binding protein G)

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8
Q

mutation in muscular dystrophy

A

dystrophin

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9
Q

doxorubicin causes

A

dilated cardiomyopathy

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10
Q

submucosal gland in GI tract

A

in esophagus and duodenum

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11
Q

differential in dexamethasone suppression

A

ACTH can’t be suppressed = ectopic source

- can be suppressed = pituitary adenoma

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12
Q

age related eye changes

A

myopia can be improved because of worsening presbyopia (patient can think diet led to an improvement)

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13
Q

part of the heart most anterior

A

right ventricle (left sternal border in fourth intercostal space)

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14
Q

stages of lobar pneumonia

A
  1. congestion
  2. red hepatization
  3. gray hepatization
  4. resolution
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15
Q

antibiotic with increase in CK and myopathy

A

daptomycin

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16
Q

MOA of daptomycin

A

similar to vanco, creates membrane channels in cell wall

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17
Q

vitamin deficiency similar to B12

A

vitamin E (also folate)

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18
Q

type of gene VHL

A

ubiquitin ligase

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19
Q

type of gene BRCA

A

DNA repair

20
Q

blood pressure med causing pulmonary edema

A

mannitol (used with caution in patients with heart failure and pulmonary edema)

21
Q

somatic symptom disorder

A

anxiety or preoccupation with one symptom

22
Q

red pulp in spleen

A

removal of defective RBCs

23
Q

cord factor

A

in TB, leads to high virulence and serpentine growth

24
Q

hydroxylation of vitamin D

A

25 in the liver, 1 in the kidney

25
Q

treatment of ophthalmopathy in graves

A

corticosteroids

26
Q

systemic infection with cryptococcus =

A

meningoencephalitis

27
Q

late complication of Fabry’s

A

renal disease

28
Q

warfarin induced skin necrosis

A

due to protein C or S deficiency (leads to prothrombotic state)

29
Q

most specific for RA

A

anti-CCP

30
Q

CFTR transporter in CF lungs

A

secretes Cl-, inhibiting sodium reabsorption by ENaC and keeping water in the lumen
- in CF, Cl- cant be secreted, so more sodium is reabsorbed and more water comes in leading to dehydrated mucus

31
Q

nerve that can be stimulated in obstructive sleep apnea

A

glossopharyngeal nerve

32
Q

antibodies in CREST

A

anti centromere

33
Q

pathway affected in fatty alcoholic steatosis

A

fatty acid oxidation leads to a build up of fat in liver

34
Q

thing associated with poorly differentiated, aggressive breast tumors

A

increased expression of HER2/Neu (tyrosine kinase)

35
Q

treatment for TCA overdose

A

sodium bicarb

36
Q

mechanism for sequelae of endocarditis

A

septic embolization

37
Q

fluctuating lymphadenopathy

A

follicular lymphoma

38
Q

DRESS lab increase

A

eosinophils and ALT

39
Q

causes of DRESS

A

anticonvulsants, allopurinol, sulfonamides, and antibiotics

40
Q

neurotransmitter decreased in Huntingtons

A

GABA

41
Q

endo vs exo nuclease

A 
endo = in middle of molecule
exo = front end of molecule
42
Q

measles can make what vitamin deficiency worse

A

vitamin A

43
Q

S3 is best heard….

A

at the end of expiration (heart is closest to chest wall)

44
Q

SA node is located

A

in the right atrium near the opening of the SVC

45
Q

encephalitis associated with flaccid paralysis

A

west nile

46
Q

CD31

A

PECAM, seen in angiosarcoma of liver

AAA - Board by day (28 decks)

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