3/24 Flashcards
cells that IL2 activates
T cells, B cells, NK cells, monocytes, helper T cells
major side effect of apmphtericin
hypokalemia and hypomagnesemia (renal dysfunction)
HELLP
hemolysis, elevated liver enzymes and lop platelets
projection
thinking your feelings are the feelings of someone else
selection bias
systemic differences between groups in terms of treatment response or prognosis, not representative of population at large
cervical cancer in a young patient
in the immunocompromised (T cell deficiency)
squatting in tetralogy of Fallot
increases systemic vascular resistance, sending more blood to lungs
superior colliculus
controls vertical gaze
painful lesion that isn’t herpes
chancroid (H dureyi) - you do cry
riluzole
for treatment of ALS
- decreases glutamate release
mutation in ALS
SOD1 - copper-zinc superoxide dismutase
antibodies in polymyositis
Anti-Jo-1 = anti-histidyl-tRNA synthetase
findings worse on chest xray than symptoms
mycoplasma (walking pneumonia)
- common in military recruits
left vs right colon tumors
- ascending = occult blood in stool
- descending = obstructive (apple core)
how cells stay bound to collagen
integrins in cell membranes bind fibronectin which binds to collagen
compound vs junctional nevus
- compound = cells have begun to move to dermis
- junctional = cells remain at dermal-epidermal junction
vessels most susceptible to atherosclerosis
abdominal aorta and coronary arteries
two tests for biliary disease
alk phos and GGTP (differentiates bone from biliary)
muscle in greater sciatic foramen
piriformis
stimulation to make TH1 cell
IFN-gamma and IL12
TH1 cells secrete…
IFN-gamma, IL2 and lymphotoxin beta
dimercaprol
treatment for arsenic poisoning (chelates heavy metals)
CaNa2EDTA
treatment of lead poisoning
deferoxamine
treatment of blood transfusions (too much iron)
hydroxycobalamin treatment
for cyanide poisoning
methylene blue
treatment of methemoglobinemia
microsomal monooxygenase
cytochrome P450 enzyme in hepatic microsomes that metabolizes things - can convert procarcinogens to carcinogens
MOA of heparin
increases activity of antithrombin III
Kussmauls sign
paradoxical increase in JVP with inspiration
- occurs due to restrictive cardiomyopathy and rarely with tamponade
pulsus paradoxus
decrease in BP during inspiration
- due to chronic contrcitive pericarditis and tamponade
pericardial knock
brief sounds shortly after S2 in patients with constrictive pericarditis
gamma interferon
activates macrophages but is produced primarily by TH1 cells
side effects of naicin
flushing warmth and itching (due to prsotaglandin release)
- can be avoided with an aspirin