38. Fatty acids Flashcards
lipids are soluble in nonpolar solvents such as
ether
chloroform
lipids are transported in the blood by
lipoproteins
fx of lipids
- storage form of energy
- impt part of diet
- thermal insulation
- electrical insulators of myelinated nerves
type of lipids:
fats, waxes
simple lipids
type of lipids:
lipoproteins
complex lipids
type of lipids:
glycolipids
complex lipids
type of lipids:
fat soluble vitamins
precursor and derived lipids
type of lipids:
fatty acids
precursor and derived lipids
long chains of carboxylic acids
fatty acids
classification of FA according to degree of saturation
saturated
monounsaturated
polyunsaturated
FA
structure :
12:0
lauric acid
FA
structure :
16:0
palmitic acid
FA
structure :
18:1(9)
oleic acid
essential FA
•linoleic acid
18:2 (9,12)
•linolenic acid
18:3 (9,12,15)
FA
structure :
20:4
(5,8,11,14)
arachidonic acid
predominant FA in coconut oil
lauric acid
end product of mammalian FA
palmitic acd
predominant FA in olive oil
oleic acid
precursor of prostaglandings, derived from linoleic acid
arachidonic acid
provide arachidonic acid, which is an important precursor of prostaglandings and leukotrienes
omega-6 fatty acids
this dietary fatty acids decrease risk of coronary heart disease
omega-6 and omega-3 fatty acids
- this dietary FA have anti-inflammaotry properties
- suppress cardiac arrhythmias, reduce serum TAGs, dec tendency for thrombosis, lower BP
- dec sudden cardiac death
omega-3 fatty acids
this dietary FA can inc risk of coronary heart disease, prostate and colon cancer
saturated fatty acids
by-product of the saturation of fatty acids during hydrogenatin of natural oils
trans fatty acids
trans FA incrisk for
coronary heart disease
diabetes mellitus
for a fatty acid to participate in metabolic processes it must first be
activated
enzyme: fatty acvyl coa synthetase
(cytosol)
