32. Hyperlipoproteinemias vs Hypolipoproteinemias Flashcards
Hyperlipoproteinemias
type I familial lipoprotein lipase deficiency type IIa familial hypercholesterolemia type III familial dysbetalipoproteinemia type IV familial hypertriacyl-glycerolemia Familia lipoprotein (a) excess Familial hyper alpha lipoproteinemia
hypoproteinemia
abetalipoproteinemia
familial alpha lipoprotein deficiency
deficiency in lipoprotein lipase or apo C-II
Type I familial lipoprotein lipase deficiency
defective LDL receptor
Type II a
Familial hypercholesterolemia
Abnormal Apo E
type III
Familial dysbetalipoproteinemia
overproduction of VLDL
type IV familial hypertriacylglycerolemia
elevated Lp(a)
familial lipoprotein (a) excess
high HDL
familial hyper alpha lipoproteinemia
defect in loading of apo B with lipid
no chylomicrons or VLDL
abetalipoproteinemia
low or near absence of HDL
familial alpha lipoprotein deficiency
caused by VLDL overproduction
Type II B: combined hyperlipidemia
Type IV: hypertriglyceridemia
Type V: Mixed hypertriglyceridemia