14. Antiobiotics Flashcards
1
Q
inhibitors of transcription
A
- rifampicin
* dactinomycin
2
Q
•inhibitors of protein synthesis
A
- streptomycin and aminoglycosides
- tetracycline
- chloramphenicol
- clindamycin and macrolides
3
Q
binds to ß subunit of DNA dependent RNA polymerase
A
rifampicin
4
Q
binds to the DNA template and interfere with the movement of RNA polymerase during transcription
A
dactinomycin
5
Q
binds with the 30S subunit and interferes with initiation
A
streptomycin and aminoglycosides
6
Q
prevents bindng of amino-acyl tRNA to the A site
A
tetracycline
7
Q
inhibits prokaryotic peptidyltransferase
A
chloramphenicol
8
Q
binds to the 50S suunit and inhibits translocation
A
clindamycin and macrolides