3/31- Specific Defenses (Exam 3) Flashcards

1
Q

What is inborn immunity?

A

Genetically determined and present at birth

Automatically defending you from specific things at birth

No previous exposure needed

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2
Q

What is acquired immunity?

A

Not present at birth

Requires exposure

2 forms

1) active
2) passive

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3
Q

What is active acquired immunity?

A

Your body is creating the defense to go after a particular threat

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4
Q

What is passive acquired immunity?

A

Defense is being passively presented to body from outside source

Taking antibodies from outside source and introducing them to a person that is either sick or in danger of getting sick

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5
Q

What is natural active acquired immunity?

A

Classic kind

Naturally occurs in the course of events

Body creates defense for particular infection

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6
Q

What is induced active acquired immunity?

A

Artificial in nature

Inducing your system to do something

Introducing infection in a weaker or dead form to body to provoke it to make a defense

Vaccines

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7
Q

What is natural passive acquired immunity?

A

Natural occurrence in childhood

Antibodies passing between mother and child in womb through placenta

Child born with maternal antibodies giving a temporary defense

Nursing also gives antibodies through breast milk

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8
Q

What is induced passive acquired immunity?

A

Artificial medical procedure

Introducing antibodies medically

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9
Q

What is gamma globulin treatment/ injection?

A

Giving patients antibodies

Ex: anti rabies antibody

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10
Q

What are 4 general properties of specific defenses?

A

1) specificity
2) versatility
3) memory
4) tolerance

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11
Q

What is specificity?

A

Defense is specific

Goes after one specific thing

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12
Q

What is versatility?

A

Body will be able to make a defense for anything

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13
Q

What is memory?

A

Immune system remembers past invaders

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14
Q

What is tolerance?

A

To ignore your own chemical signatures

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15
Q

How do specific defenses be?

A

Shape of receptors in cell membrane match certain chemicals

To attack an invader receptor shape and invader shape have to match exactly

You were introduced to your chemical signatures at birth

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16
Q

What are memory cells?

A

Lymphocytes clone when invader is invading

Half of cells don’t fight and become memory cells

There to be prepared and ready if the same invader shows up again

Can live up to 20 years

17
Q

What is an antigen?

A

Any chemical that provoked an immune response

18
Q

What are the 3 things cytotoxic T cells do to destroy invading cells?

A

1) Perforin- creates wholes in cell membrane
2) Lymphotoxin- disrupted metabolism of invading cell (lymphocytes poison)
3) Cytokine- commands apoptosis

19
Q

What is humors?

A

Any bodily fluid

Blood
Lymph
Saliva
Urine

20
Q

What are the 5 types of immunoglobulin (Ig)?

A

1) IgG
2) IgM
3) IgA
4) IgD
5) IgE

21
Q

What are immunoglobulins made of?

A

4 polypeptide chains (quaternary structure)

2 heavy chains (H chain)
2 light chains (L chain)

22
Q

What is a variable region?

A

Different shape receptors

Each population of B cells produce different variable region matching invaders

Interacts with the invader

23
Q

What is the constant region?

A

All B cell population produces constant region exactly the same

Interacts with your cells

24
Q

What is primary response?

A

First response when there is an invader

Gets you sick

Memory cells are created

25
Q

What is a secondary response?

A

When invader appears in the future no matter how many times

Not even aware you are infected again

Fought off immediately

Memory cells are ready for invader

26
Q

What are the 3 categories of malfunctions in immune system?

A

1) Autoimmune Disorders
2) Immunodeficiency Disease
3) Allergies

27
Q

What are autoimmune disorders?

A

Persons immune system attacks itself

Specific defenses

Disease depends on the target cells attack

28
Q

What are selfantigens?

A

One or more of your chemical start to act like antigen

29
Q

What are autoantibodies?

A

Antibodies that attack self

30
Q

What are 3 causes of immunodeficiency diseases?

A

1) Embryological Development Issue- lymphatic tissue or lymphoid organ doesn’t develop
2) viruses that attack your immune system (helper T cells)- Ex: HIV
3) immunosuppressive agents- suppresses lymphocytes and function of immune system

31
Q

What are allergies or hypersensitivity?

A

Immune system overreacts

Allergens- antigens

2 kinds

1) immediate hypersensitivity
2) delayed hypersensitivity

32
Q

What is immediate hypersensitivity?

A

B cell (antibody) issue

Get a reaction immediately

Histamine is released

Antihistamine- treatment

33
Q

What is anaphylaxis?

A

Allergen gets into blood stream and circulates everywhere

Releases histamine everywhere- diamanté’s blood vessels

Can go into anaphylactic shock

34
Q

What is anaphylactic shock?

A

Life threatening

Needs Epi Pen

Blood pressure decreases fast

35
Q

What is flare and wheal reaction?

A

Happens at allergist when you have a reaction to something they injected

Flare- redness from dilated blood vessels

Wheal- raises flat bump- edema

Due to release of histamine

36
Q

What is delayed hypersensitivity?

A

Due to reaction of T cells take awhile to get there

Treatment- cortisol or hydrocortisone (corticosteroids)

Ex: skin rashes like poison ivy

37
Q

What is the complement system in specific defenses?

A

When it works with antibodies