26 Chemical Therapy

Question 1

Cisplatin

Answer 1

鉑家族，烷化劑
易嘔吐，用Ondansetron治療
小心腎功能

Question 2

Carboplatin

Answer 2

鉑家族，烷化劑

易嘔吐，用Ondansetron治療

Question 3

Oxaliplatin

Answer 3

鉑家族，烷化劑

易嘔吐，用Ondansetron治療

Question 4

Cyclophosphamide

Answer 4

Mechlorethamine, 烷化劑一種

會造成出血性膀胱炎，以 Mesna 預防

Question 5

Mercaptopurine

Answer 5

Purine antagonist 影響 S phase

Question 6

Fluorouracil (5-FU)

Answer 6

Pyrimidine antagonist

可抑制 thymidylate synthase

Question 7

Cytarabine

Answer 7

Pyrimidine antagonist

可抑制 DNA polymerase

Question 8

Methotrexate (MTX)

Answer 8

模仿葉酸，抑制 Dihydrofolate reductase

Question 9

Irinotecan

Answer 9

Topoisomerase I inhibitor

Question 10

Daunorubicin

Answer 10

Anthracycline 類
Topoisomerase II inhibitor
不可 IV，外滲會皮膚壞死，要冰敷

Question 11

Doxorubicin

Answer 11

Anthracycline 類
Topoisomerase II inhibitor
不可 IV，外滲會皮膚壞死，要冰敷

Question 12

Epirubicin

Answer 12

Anthracycline 類
Topoisomerase II inhibitor
不可 IV，外滲會皮膚壞死，要冰敷

Question 13

Idarubicin

Answer 13

Anthracycline 類
Topoisomerase II inhibitor
不可 IV，外滲會皮膚壞死，要冰敷

Question 14

Etoposide

Answer 14

Topoisomerase II inhibitor

可能造成骨髓抑制

Question 15

Vinblastine

Answer 15

Antimicrotubule agents

不能用 IV, 外滲要熱敷

Question 16

Vincristine

Answer 16

Antimicrotubule agents

不能用 IV, 外滲要熱敷

Question 17

Paclitaxel

Answer 17

微管抑制劑

Question 18

Docetaxel

Answer 18

微管抑制劑