24 Autonomic Nervous System Flashcards
Trimethaphan
Ganglionic blocker
IV治療惡性高血壓
Mecamylamine
Ganglionic blocker
PO治療惡性高血壓
Reserpine
Indirect-acting adrenergic blocker
抑制 dopamine 攝入小泡
用來降血壓,但會致鬱
Guanethidine
Indirect-acting adrenergic blocker
抑制 Vesicle 內 Neurotransmitter 釋放至突觸間隙
用來降血壓
Ephedrine
Indirect-acting adrenergic agonist
促進 Vesicle 內 Neurotransmitter 釋放
口服治療鼻塞、尿床
Amphetamine
Indirect-acting adrenergic agonist
促進 Vesicle 內 Neurotransmitter 釋放
較易進入中樞,造成情緒亢奮、食慾抑制
Methylphenidate
Amphetamine 一種
治療過動兒
Phenylpropanolamine (PPA)
Amphetamine 一種,抑制食慾幫助減肥
Amitriptyline (TCA)
Indirect-acting adrenergic agonist
抑制 NE, serotonin reuptake
治療憂鬱症
Hemicholinium
Indirect-acting cholinergic blocker
抑制 choline 攝入(ACh 原料)
Botulism
Indirect-acting cholinergic blocker
抑制 ACh 釋放到突觸
用於除皺、肌肉鬆弛
Neostigmine
Indirect-acting cholinergic agonist
抑制 ACh 被 AChE 分解
治療術後腸阻塞、重症肌無力
Physostigmine
Indirect-acting cholinergic agonist
抑制 ACh 被 AChE 分解
可過 BBB,治療青光眼
Epinephrine
Mixed adrenergic agonist (α, β1, β2)
過敏性休克
Norepinephrine
Mixed adrenergic agonist (α, β1)
治療低血壓,但腎灌流會下降
Dopamine
Mixed adrenergic agonist (D>β>α)
治療低血壓,且不影響腎灌流
Midodrine
α1 agonist
治療姿勢性低血壓
Phenylephrine
α1 agonist
散瞳劑、治療鼻塞
Clonidine
α2 agonist
治療腎不好的高血壓,但突然停藥會有 rebound HTN
Methyldopa
α2 agonist
治療孕婦高血壓,突然停藥會有 rebound HTN