23 Endocrine System

Question 1

Octreotide

Answer 1

GH antagonist

治療末端肥大症、巨人症

Question 2

Bromocriptine

Answer 2

Dopamine agonist

治療 Prolactinoma before surgery

Question 3

Terlipressin

Answer 3

V1 agonist (Vasopressin)
可收縮血管，治療食道靜脈瘤急性出血

Question 4

Desmopressin

Answer 4

V2 agonist
抗利尿，防止小孩尿床、治療中樞尿崩症
也可促進凝血因子 VIII, vWF

Question 5

Demeclocycline

Answer 5

ADH antagonist

利尿劑，治療 CHF, SIADH

Question 6

Liothyronine

Answer 6

T3, 作用太強副作用大，現在少用

治療甲狀腺低下

Question 7

Levothyroxine

Answer 7

T4, 可被轉換成 T3，常用

治療甲狀腺低下

Question 8

Liotrix

Answer 8

T3: T4 = 1:4

治療甲狀腺低下

Question 9

Methimazole

Answer 9

Thioamides, 抑制甲狀腺素合成（所以要三到四週才有效）
治療 Hyperthyroidism
副作用：皮疹、白血球過低
孕婦不能用

Question 10

Propylthiouracil (PTU)

Answer 10

Thioamides, 抑制甲狀腺素合成（所以要三到四週才有效）
治療 Hyperthyroidism
副作用：皮疹、白血球過低
孕婦能用

Question 11

Carbimazole

Answer 11

Thioamides, 抑制甲狀腺素合成（所以要三到四週才有效）

治療 Hyperthyroidism

Question 12

Iodide

Answer 12

利用高劑量碘負回饋治療甲狀腺機能亢進

急救用（Thyroid storm）

Question 13

Thyroid storm treatment

Answer 13

PTU, Iodide, β blocker, Dexmethasone

Question 14

Perchlorate

Answer 14

Iodide uptake inhibitor

治療 amiodarone-induced hyperthyroidism

Question 15

Pertechnetate

Answer 15

Iodide uptake inhibitor

治療 amiodarone-induced hyperthyroidism

Question 16

Iohexol

Answer 16

抑制 T4 轉換成 T3，輔助治療 Thyroid storm

Question 17

Diaztrizoate

Answer 17

抑制 T4 轉換成 T3，輔助治療 Thyroid storm

Question 18

Alendronate

Answer 18

雙磷酸鹽，治療骨質疏鬆

吃完不能馬上躺平會食道潰瘍

Question 19

Risedronate

Answer 19

雙磷酸鹽，治療骨質疏鬆

吃完不能馬上躺平會食道潰瘍

Question 20

Raloxifene

Answer 20

SERM, 預防骨質疏鬆

Question 21

Calcitonin

Answer 21

抑制蝕骨細胞，促進成骨細胞

Question 22

Denosumab

Answer 22

Anti-RANKL，抑制蝕骨細胞

Question 23

Teriparatide

Answer 23

Recombinant hPTH，促進成骨細胞

Question 24

Romosozumab

Answer 24

Anti-sclerostin （IgG2）

Question 25

Mecasermin

Answer 25

Recombinant human IGF-1