2. MTB Step 3 - COPD/Emphysema Flashcards

Cards Complete Day 1: 4/30/19 * Day 2: 5/2/19 * Day 3: 5/10/19 * Day 4: 5/30/19 Day 5: 6/29/19

1
Q

PRESENTATION

What are (3) Common HPI Findings for COPD/Emphysema?

A
  1. Increased Shortness of Breath (SOB)
  2. In a Long-term Smoker
  3. With Decreased Exercise Tolerance
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2
Q

MANAGEMENT

What is the ONLY way to Assess CO2 Retention in COPD/Emphysema (and therefore Critical that you perform in ALL patients presenting with Acute SOB)?

A

Arterial Blood Gas (ABG)

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3
Q

MANAGEMENT

Acute episodes of Shortness of Breath (SOB) should be handled with which (4) Treatments?

A
  1. Albuterol (inhaled)
  2. Methylprednisolone (bolus)
  3. Ipratropium (inhaled)
  4. Oxygen
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4
Q

MANAGEMENT

Acute episodes of Shortness of Breath (SOB) should receive which (3) Diagnostic Exams?

A
  1. Chest X-Ray (CXR)
  2. Arterial Blood Gas (ABG)
  3. Chest, Heart, Extremity, & Neurologic exams
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5
Q

MANAGEMENT

If Fever, Sputum, or new Infiltrate are present in a patient who also presents with Acute Shortness of Breath (SOB) which (2) Antibiotics should be Added, and Why?

A

add Ceftriaxone and Azithromycin for Community-Acquired Pneumonia (CAP)

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6
Q

MANAGEMENT

On CCS, why should you move the clock forward 15 - 30 minutes and Reassess AFTER giving Oxygen to a patient with COPD/Emphysema?

A

Oxygen may Worsen SOB in a patient with COPD by Eliminating Hypoxic Drive

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7
Q

MANAGEMENT

Why should you NOT Intubate a patient with COPD solely due to CO2 Retention?

A
  • These patients often have Chronic CO2 Retention.
  • ONLY Intubate if there is a Worsening in pH i_ndicative of_ a WORSE Respiratory Acidosis.
  • Serum bicarbonate is often elevated due to metabolic alkalosis as compensation for chronic respiratory acidosis.
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8
Q

FURTHER MANAGEMENT (IN OFFICE)

What are (5) Important Physical Findings in a patient with Chronic COPD/Emphysema?

A
  1. Barrell-shaped Chest
  2. Clubbing of Fingers
  3. Increased AP Diameter of Chest
  4. Loud P2 sound (sign of Pulmonary HTN)
  5. Edema (Decreased RV output due to Pulmonary HTN)
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9
Q

FURTHER MANAGEMENT (IN OFFICE)

What are (3) ECG Findings in a patient with Chronic COPD?

A
  1. Right Axis Deviation (RAD)
  2. Right Ventricular Hypertrophy (RVH)
  3. Right Atrial Hypertrophy (RAH)
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10
Q

FURTHER MANAGEMENT (IN OFFICE)

What are (3) CXR Findings in a patient with Chronic COPD/Emphysema?

A
  1. Flattening of Diaphragm (due to hyperinflation of lungs)
  2. Elongated Heart
  3. Substernal Air Trapping
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11
Q

FURTHER MANAGEMENT (IN OFFICE)

What are (2) CBC Findings in a patient with Chronic COPD/Emphysema?

A
  1. Increased Hematocrit
  2. Microcytic Reactive Erythrocytosis from Chronic Hypoxia
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12
Q

FURTHER MANAGEMENT (IN OFFICE)

What is (1) Chemistry Panel Finding in a patient with Chronic COPD/Emphysema?

A
  1. Increased Serum Bicarbonate due to Metabolic Compensation for Respiratory Acidosis.
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13
Q

FURTHER MANAGEMENT (IN OFFICE)

What are (2) ABG Findings in a patient with Chronic COPD/Emphysema?

A
  1. Increase in pCO2
  2. Decrease in pO2
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14
Q

FURTHER MANAGEMENT (IN OFFICE)

What is meant by “being a member of the 50/50 club” in a patient with Chronic COPD/Emphysema?

A

the pCO2 is ~50 mmHg and the pO2 is also ~50 mmHg.

Example ABG for a patient with COPD:

  • pH: 7.35
  • pCO2 : 49
  • pO2 : 52
  • HCO3 : 32
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15
Q

FURTHER MANAGEMENT (IN OFFICE)

What is the Mechanism of Right Heart Enlargement in COPD/Emphysema?

A
  • Hypoxia in the lungs causes capillary constriction, in which precapillary sphincters in the lungs constrict to shunt blood away from hypoxic areas of the lung.
  • Since the hypoxia of COPD is global throughout the lung, this diffuse vasoconstriction increases pressure in the right ventricle and right atrium.
  • Over time, the result is hypertrophy of both chambers, leading to cor pulmonale, or right heart failure.
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16
Q

FURTHER MANAGEMENT (IN OFFICE)

What Pulmonary Function Test (PFT) Findings should you expect on the following measures in a patient with COPD/Emphysema?

  • Forced Expiratory Volume 1 (FEV1)
  • Functional Vital Capacity (FVC)
  • FEV1/FVC Ratio
  • Total Lung Capacity (TLC)
  • Residual Volume
  • DLCO
A
  • ↓ Forced Expiratory Volume 1 (FEV1)
  • ↓ Functional Vital Capacity (FVC)
  • ↓ FEV1/FVC Ratio
  • ↑ Total Lung Capacity (TLC)
  • ↑ Residual Volume
  • ↓ DLCO
17
Q

CHRONIC MEDICAL THERAPY FOR COPD

What are (5) Antimuscarinic Medications (LAMAs) used in the Treatment of Chronic COPD/Emphysema?

A
  1. Tiotropium
  2. Ipratropium
  3. Aclidinium
  4. Umeclidinium
  5. Glycopyrrolate
18
Q

CHRONIC MEDICAL THERAPY FOR COPD

What is (1) Short-Acting Beta-Agonist (SABA) used in the Treatment of Chronic COPD/Emphysema?

A

Albuterol (Inhaler)

19
Q

CHRONIC MEDICAL THERAPY FOR COPD

What are (5) Long-Acting Beta-Agonists used in the Treatment of Chronic COPD/Emphysema, but should NEVER be used alone?

A
  1. Salmeterol
  2. Formoterol
  3. Indacaterol
  4. Olodaterol
  5. Vilanterol
20
Q

CHRONIC MEDICAL THERAPY FOR COPD

What are the (2) Pneumococcal Vaccinations given to ALL patients with Chronic COPD/Emphysema and when are they given?

A

13-Polyvalent = to start

then

23-Polyvalent = 1 yr later

21
Q

CHRONIC MEDICAL THERAPY FOR COPD

What is the (1) Influenza Vaccination given to ALL patients with Chronic COPD/Emphysema?

A

Inactivated Vaccine: yearly

22
Q

CHRONIC MEDICAL THERAPY FOR COPD

What are the (2) Criteria for Long-Term Home Oxygen in patients with Chronic COPD/Emphysema?

A

pO2 < 55 mmHg

or

O2 Saturation < 88%

23
Q

CHRONIC MEDICAL THERAPY FOR COPD

What is the (1) Phosphodiesterase (PDE) Inhibitor medication given to patients with Chronic COPD/Emphysema?

A

Roflumilast

  • a PDE Inhibitor that provides a modest Anti-inflammatory effect and Relaxes smooth muscle.
  • The answer is Roflumilast ONLY when the question describes a patient who is still symptomatic despite SABAs, LABAs, LAMAs, and Inhaled Steroids.
24
Q

CHRONIC MEDICAL THERAPY FOR COPD

What is the Mechanism of Bicarbonate Increase in COPD/Emphysema?

A
  • COPD generates CO2 Retention.
  • CO2 Retention generates Respiratory Acidosis.
  • Chronic Respiratory Acidosis INCREASES new Bicarbonate generation at the Distal Tubule of the Kidney.

COPD = Bicarbonate Increase