1.8 MTB Step 3 - The Newborn (Teratogenesis) Flashcards

1
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (2) Adverse Effects of both Anesthetics & Barbiturates?

A
  1. Respiratory Depression
  2. CNS Depression
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2
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of Magnesium Sulfate?

A

Respiratory Depression

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3
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of Phenobarbital?

A

Vitamin K Deficiency

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4
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of Sulfonamides?

A

Displaces Bilirubin from Albumin

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5
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of NSAIDs?

A

Premature Closure of Ductus Arteriosis

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6
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of ACE Inhibitors?

A

Craniofacial Abnormalities

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7
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (2) Adverse Effects of Isotretinoin?

A
  1. Facial and Ear anomalies
  2. Congenital Heart Disease
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8
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (3) Adverse Effects of Phenytoin?

A
  1. Hypoplastic Nails
  2. Typical Facies
  3. IUGR
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9
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of Diethylstilbestrol (DES)?

A

Vaginal Adenocarcinoma

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10
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (2) Adverse Effects of Tetracycline?

A
  1. Enamel Hypoplasia
  2. Discolored Teeth
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11
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What is (1) Adverse Effect of Lithium?

A

Ebstein Anomaly

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12
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (2) Adverse Effects of Warfarin?

A
  1. Facial Dysmorphism
  2. Chondrodysplasia (Bone Stippling)
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13
Q

TERATOGENESIS & THE EFFECT OF DRUGS ON THE NEONATE

What are (2) Adverse Effects of Valproate/Carbamazepine?

A
  1. Mental Retardation
  2. Neural Tube Defects (NTDs)
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