Zoonoses III Flashcards

1
Q

what is Q fever due to? and how is it transmitted?

A

Due to Coxiella Burnetti

inhalation

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2
Q

reservoirs of Q fever

A

sheep, cattle, goat

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3
Q

phases of coxiella burnetti

A

phase I: highly infectious with intact LPS

phase II: not infectious with truncated LPS

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4
Q

symptoms in acute phase of Q fever

A

fever, chills, headache, rash, pneumonia, hepatitis

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5
Q

symptoms in chronic phases of Q fever

A

most important is endocarditis

osteomyelitis, and encephalitis

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6
Q

how to diagnose Q fever

A

IgM peak at 4 to 6 weeks

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7
Q

virus in korean hemorrhagic fever

A

hantaan virus

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8
Q

animal associated with koran hemorrhagic fever

A

deer mouse (most important) and rat

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9
Q

what is the severe pulmonary syndrome in korean hemorrhagic fever called

A

sin nombre

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10
Q

manifestation of Korean Hemorrhagic fever

A

interstitial edema, respiratory failure, death

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11
Q

diagnosis of korean hemorrhagic fever

A

RT-PCR

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12
Q

species of toxocariasis and the associated animals

A

toxocara canis - dogs

toxocara cati - cats

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13
Q

how does one get toxocariasis

A

children typically who are exposed or ingest contaminated soil

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14
Q

clinical syndromes of toxocariasis

A

visceral toxocariasis - fever, coughing, enlarged liver, pneumonia

ocular toxocariasis - larvae travels to eye and causes inflammation and scarring of retina leading to irreversible vision loss that is uniocular

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15
Q

prevention of toxocariasis

A
  • wash hands especially after playing outside
  • kids stay away from contaminated sandboxes
  • dispose of animal feces properly
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16
Q

how does one get toxoplasmosis

A
  • eating undercooked meat
  • exposure to cats
  • drinking raw milk
17
Q

how done one get immune to toxoplasmosis

A

getting infection then eventually building lifelong immunity via elevated IgG

18
Q

population most at risk for toxoplasmosis

A

AIDS - chorioretinitis (seen in others as well)

pregnant women because it can cause hydrocephalus in baby via vertical transmission

19
Q

how to diagnose toxoplasmosis

A

PCR

20
Q

ixodes tick bite is associated with what disease

A

lyme disease and bebesiosis

21
Q

organism in lyme disease

A

borriela burgdorferi

22
Q

what must be avoided if one has lyme disease

A

red meat

23
Q

why must one avoid red meat if they have lyme disease

A

lone star tick carries sugar called alpha gal (also found in red meat) and once bitten body builds antibodies against the sugar

so once someone someone eat red meat, there is an allergic reaction - Type I HS

24
Q

when is the most infectious stage of deer tick and why

A

during spring or summer because during fall larvae requires blood meal to develop into a nymph in which they stay dormant all throughout the winter.

during spring or summer, nymphs need another blood meal to become adults

25
Q

what in mammalian causes the activation of microorganism within the tick and what happens thereafter

A

the higher temp of mammalians activates the microorganism which then multiplies and penetrates the gut wall then spreads to the salivary gland of the tick

26
Q

what is seen in the various stages of lyme disease

A

primary: ECM - erythema chronicum migrans
secondary: secondary annular skin lesions aka exanthems
tertiary: ACA and CNS symptoms

27
Q

how does one see ricketsii

A

giemsa staining

28
Q

common symptoms of rickettsial infections

A

severe retro orbital headaches
rash
fever

29
Q

mode of transmission and reservoir of rickettsii ricketsii aka rocky mountains spotted fever

A

tick bite

dogs

30
Q

symptoms of spotted fever and what happens if left untreated

A

centripetal spread of rash - starts at wrist and goes to trunk then back down to extremities including sole of feet and palms of hands

become fatal - DIC, vascular collapse, renal and heart failure

31
Q

microorganism in scrub typhus and mode of transmission

A

orientia tsutsugamushi

mites

32
Q

symptoms seen in scrub typhus

A

maculo papular rash that includes sole of feet and palms of hands, renal failure, hemorrhage, death

33
Q

species of ehrlichiosis

A

e. canis and e. chafeensis

34
Q

how is ehrlichiosis transmitted

A

brown dog tick

35
Q

what is ehrlichiosis often confused with

A

rocky mountain spotted fever

36
Q

specie of anaplasmosis and what transmits it

A

anaplasma phagocytophilum and it is tick borne

37
Q

animal associated with viral hemorrhagic fever syndrome

A

rats

38
Q

type of damage is seen in viral hemorrhagic fever syndrome

A

damage to vascular system

39
Q

four families of virus associated with viral hemorrhagic fever syndrome

A

arena, bunya, flavi, filo