Fungal Infections II Flashcards

1
Q

why is it so difficult to treat tinea unguium and what is best treatment

A

using topical treatments don’t work because it cannot penetrate the nail plate into the nail bed where the fungus resides

best to treat with oral systemic antifungal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what does epidermophyton attack and what is the only pathogenic species in this genus

A

skin and nails

e. floccosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is seen on agar of epidermophyton

A

just macroconidia which are smooth walled and large – born singly or in banana shaped clusters

no microconidia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what does microsporum attack and what is seen on agat

A

skin and hair

see more macroconidia than microconidia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

treatments for dermatophytes

A
orally active triazoles
allylamines (terbinafine)
griseofulvin and ketoconazole
thiocarbonates (tolnaftate)
many imidazoles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are control measure for opportunistic fungi like candida and molds

A
  • discontinue antibiotics and restore normal flora
  • restore immune system
  • surgical removal of lesions and antimicrobials
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most common mold in externa otitis

A

aspergillus species

next is fusarium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

where do skin infections with candida usually occur

A

moist areas like between toes, folds of skin obese patients, diaper rash in infants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

prevention of candidiasis of the skin

A
  • clotrimazole or nystatin
  • disposable diapers
  • decrease moisture and chronic trauma in babies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is Hyalohyphomycosis

A

generic name for many species of non black mold fungal infections but aspergillosis just so common that it has its own category

fusarium is an example of hyalohyphomycosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is Phaeohyphomycosis

A

term for black mold fungal infections not covered by older historical names like tinea nigra and such

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are chronic subcutaneous infection caused by

A

fungi or bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is another name for chromoblastomycosis (which is in fact a type of phaeophyphomycosis)

A

verrucous dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

causative agent of chromoblastomycosis

A

black pigmented soil fungi –> philalophora and cladosporium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

clinical presentation of chromoblastomycosis

A

wart like nodules that are slow growing and painless

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

most common fungal agent of eumycetoma

A

Pseudoallescheria boydii (Petriellidium boydii).

17
Q

another name for eumycetoma

A

madura foot

18
Q

how does eumycetoma/madura foot present

A

local swelling with suppuration and abscess formation

19
Q

what is causative agent of sporotrichosis

A

Sporothrix schenckii.

20
Q

how does one get infected by sporothrix schenckii

A

infection by splinters, thorns, and cuts of the skin

21
Q

how do you treat sporotrichosis

A

oral potassium iodide (in milk)

22
Q

how does sporothrix schenckii look like on microscopy

A

flower like sporulation

23
Q

what predisposes one to fusarium

A

scatches, contact lenses

since this is an eye infection

24
Q

with a wood’s light (UV) exam what do you see with tinea versicolor

A

fluoresces subtle gold colors

25
with a wood's light (UV) exam what do you see with tinea capitis and what is the limit
fluoresces a ligher greenish blue only if it is the microsporum canis and microsporum audouinii species causing
26
what do you see with UV exam if tinea capitis is caused by trichophyton
no fluorescence -- this will be the case for most tinea capitis since trichophyton is the most common agent
27
yeast infections in blood take how long to culture
2-7days
28
dimorphic fungi take how long to blood culture
2-6 weeks
29
what temp does mycobacterium marinum require to grow
28-30oC
30
what does mycobacterium marinum look like when exposed to light
yellow pigment (it is an acid fast photochromogen)
31
how can you identify mycobacterium marinum when clinically presented to you
cuts and abrasions of the skin usually hands while working in or around sea water or aquarium water
32
features of mycobacerium ulcers
- slow growing non photochromogen - requires 28-30oC to culture - commonly known as Buruli ulcer
33
what does mycobacterium chelonae cause
soft tissue abscesses and chronic cutaneous lesions
34
what is mycobacerium chelonae associated with
implants derived from living tissue
35
how do you treat m. chelonae
surgical excision plus cefoxitin and amikacin