Hepatitis II Flashcards
what does large form HDAg do
- suppresses HBV replication
- packages the HDV genome
what does small form HDAg do
transactivating the replication of HDV genome
what marker is elevated in Hep D
alanine amino transferase ALT
also high in Hep C
what does infection with Hep D interfere with
activation of an early step in the JAK STAT signal transduction pathway
how is Hep D diagnosed and control
anti delta IgM or anti delta IgG
control by controlling Hep B with vaccination
treatment of Hep D
higher doses of longer duration of IFNalpha
IFNalpha destroys RNA which is the genome of Hep D
which of the hepatitis has a high mortality in pregnant women
Hep E
does Hep E develop into fulminant hepatitis
it is usually self limiting and very seldom does it develop into fulminant hepatitis
treatment of Hep E
inteferon and ribavirin
type of hepatitis caused by Hep G
syncytial giant cell hepatitis
transfusion transmitted hepatitis
Hep TT and Hep C
genome in Yellow Virus
flavivirus so +ssRNA
where is yellow virus common and how is it transmitted
Africa - aedes aegypti mosquitoes
South America - haemagogus mosquitoes
clinical features of yellow virus
within a week, abrupt fever, myalgia, prostration and it resolves in 5 days
clinical features seen in severe yellow virus infection
fever, jaundice, bleeding seen with hematemesis, collapse
