Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Womens Health Drugs > Flashcards

Womens Health Drugs Flashcards

1
Q

What is the first phase of the ovarian cycle?

A

Follicular phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the first 2 phases of the uterine cycle?

A

Menses

Proliferation phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the 2nd phase of the ovarian cycle?

A

Luteal phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the 3rd phase of the uterine cycle?

A

Secretory phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What phase contains the highest levels of progesterone levels?

A

Luteal/secretory phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What phase is estrogen increasing?

A

Follicular/Proliferation phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What causes LH and FSH to increase at the beginning of follicular phase?

A

Slow rise in estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the MOA of BC how does it effect ovulation?

A

Large dose of estrogen and progesterone cause a negative feedback to LH and FSH…causing no ovulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the 6 major effects of estrogen on the body?

A 
Increase risk for VTE
Increase bone retention
Increase in female body contours
Cervical mucus thinning
Increase risk for endometrial cancer
Increase risk for breast cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 5 major effects of progesterone on the body?

A 
Increase risk for VTE
Increase bone retention
Thickening of cervical mucus
Increase in alveolar growth
Inhibition of uterine contractions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is RU 486? what is it used for?

A

Progesterone agonist

Used to abort fetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the major estrogen that comes from the body?

A

Estradiol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does the body use to make estrogen and progesterone? What is the basically chemical structure of the sex hormones considered? How does it cross the cell membrane?

A

Cholesterol

Steroid

Simple diffusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the good factors from taking exogenous estrogen? Bad factors?

A

Decreases hot flashes
Increases bone retention

Increases cancer risk
Increases VTE risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the indications for Estrogen(7)?

A 
Atrophic vaginitis
Hypogonadism
BC
uterine bleeding
Hot flashes
Osteoporosis
Ovary removal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is dyspareunia?

A

Pain during intercourse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is atrophic vaginitis?

A

Shrinkage of vagina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is hypogonadism?

A

Decrease in the production of estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the contraindications for estrogen(5)?

A 
Allergy
Estrogen dependent cancer
Abnormal vaginal bleed
Pregnant
VTE risk
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are ADR of estrogens?

A 
VTE
N/V
chloasma 
Amenorrhea 
HA
Fluid retention
Tender breasts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Which pts are not recommended for estrogen HRT?

A

Pts with endometrial cancer or breast cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What must be assessed in pts who have had several years use of estrogen HRT?

A

Bone mineral density

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What do progestin drugs have in their name?

A

-gest- or nor-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What are the indications for progestins?

A 
Uterine bleeding
Amenorrhea
Uterine cancer
BC
prevention of threatened miscarriage
PMS Sx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What can uterine bleeds be caused by?

A

Hormone imbalance
Fibroids
Uterine cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What are fibroids?

A

Non cancerous growth in uterus

27
Q

What are the ADRs of Progestins?

A 
Cholesterol jaundice 
VTE
N/V
Amenorrhea
Edema
28
Q

What is cholestatic jaundice? What Sx does it cause?

A

Bile duct gets blocked which increases bilirubin deposited in skin

Causes severe itching

29
Q

What effect does hypocalcemia cause on nerves?

A

Increases the frequency of AP

30
Q

How does Calcitonin effect Ca2+ in the blood?

A

Decreases Ca2+ in the blood

31
Q

How does PTH effect Ca2+ in the blood?

A

Increases Ca2+ in the blood

32
Q

What effect do osteoclasts have on Ca2+ in the blood?

A

Increase Ca2+ in blood

33
Q

What I needed for Ca2+ to be reabsorbed in the kidneys and be absorbed in the intestines?

A

Vitamin D

34
Q

What conditions can cause hypocalcemia(6)?

A 
Vit D deficiency
Calcitonin secreting thyroid tumors
Dialysis
Diarrhea
Pregnancy
Hypoparathyroidism
35
Q

Why does dialysis and diarrhea cause hypocalcemia?

A

Because you poop and pee out Ca2+

36
Q

Why does pregnancy cause hypocalcemia?

A

Because creating a skeleton inside of you requires increased demand for Ca2+

37
Q

Why does hypoparathyroidism cause hypocalcemia?

A

Because of the decreased production of PTH which increases Ca2+ in the blood

38
Q

What are the 2 Tx options for hypocalcemia? What are their ADR?

A

Calcium supplements
Vit D

Lead to kidney stones

39
Q

What syndrome can be caused by hypocalcemia? How can you Tx this condition?

A

Carpopedal syndrome

Ca2+ IV

40
Q

What causes hypercalcemia?

A

Renal dysnfunction
Multiple myeloma
Parathyroid tumor

41
Q

How does renal dysfunction cause hypercalcemia?

A

Causes too much reabsorption of Ca2+

42
Q

How does multiple myeloma cause hypercalcemia?

A

Multi myeloma causes cytokines to be released to increase osteoclasts activity

43
Q

Why does parathyroid tumor cause hypercalcemia?

A

Because the tumor secretes increased amounts of PTH

44
Q

What does a RANKL and RANK interaction cause?

A

Increase in osteoclasts activity

45
Q

What holds RANKL? What holds RANK? What does it activate and turn it into?

A

Osteochondral progenitor/osteoblast

Osteoclasts precursor

RANKL and RANK interaction activate NFKB in precursor cell and turn it into a osteoclast

46
Q

What prevents RANKL and RANK interactions?

A

OPG binds to RANKL to prevent RANK from binding

47
Q

What increases OPG production? Decreases?

A

Increases

  • mechanical strain
  • sex hormones

Decreases

  • PTH
  • Glucocorticoids
48
Q

What increases RANKL expression? Decreases?

A

Increases

  • PTH
  • glucocorticoids

Decreases
-sex hormones

49
Q

What is osteoporosis? How many SD away <30yo? What comes before osteoporosis? How many SD away <30yo?

A

Decreased BMD
-1 SD

Osteopenia
-2.5 SD

50
Q

What is the female athlete triad?

A
  1. decreased food intake
  2. Increased number calories being burned
  3. decreased body weight which decreases Estrogen levels
51
Q

Pain in osteoporosis is associated with what?

A

Pain is associated with fractures

52
Q

What are common fractures for pt with osteoporosis(5)?

A 
Hip
Vertebrae
Pelvis
Humerus
Distal radius
53
Q

What are personal characteristics that can lead to osteoporosis(5)?

A 
Increased age
Female
White or Asian
Low body weight
Postmenopausal
54
Q

What are lifestyles that can increase risk for osteoporosis?

A

Sendentary

Ca2+/vit D deficiency

55
Q

What drugs/diseases can cause osteoporosis?

A

Corticosteroids/cushings disease
Celiac disease
Anorexia nervosa

56
Q

How does celiac disease cause osteoporosis?

A

Because it decreases the bodies ability to absorb Ca2+

57
Q

Before giving a uterine stimulant, what should be assessed? How can this effect the fetus

A

Mother and fetus vitals

Can increase fetal HR

58
Q

What are uterine stimulants called?

A

Oxytocics

59
Q

What are uterine relaxants called?

A

Tocolytics

60
Q

What are Sx of hypercalcemia?

A

N/V
constipation
Lethargy
Muscle weakness

61
Q

What is the #1 drug to Tx osteoporosis?

A

Bisphosphonate

62
Q

What is the synthetic version of oxytocin?

A

Pitocin

63
Q

What is a common ADR of OCPs?

A

N/V

Pharmacology (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions