WEEK 5 END OF WEEK FORMATIVE Flashcards
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D - 5mg of folic acid taken from before and until 3 months after conception to reduce the risk of spina bifida
What is the normal folic acid taken during pregnancy? What positive benefit may taking folic acid throughout pregnancy give in epilepsy patients?
Normal folic acid - 400mcg through trying to get pregnant and up to 3months post-conception In epilepsy patients, may benefit from taking folic acid throughout pregnancy to prevent folate deficiency anaemia
What is the difference of pharmacokinetics and pharmacodynamics? What are the four areas of pharmacokinetics?
Pharmacokinetics - the effect the body has on the drug Absorption, distribution, metabolism, elimination Pharmacodynamics- he effect the drug has on the body
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A - the volume of drug distribution is increased by changes in plasma volume and fat stores
How is absorption affected in pregnancy? How is distribution affected in pregnancy? How is metabolism affected in pregnancy? How is elimination affected in pregnancy?
* Absorption - morning sickness and nausea may affect drug absorption during pregnancy * Distribution - there is more free circulating drugs due to reduced protein binding Also the volume of drug distribution is increased due to changes in plasma volume and fat stores * Metabolism - the liver metabolism of some drugs is increased * Elimination - GFR is increased, therefore elimination of renally excreted drugs increases
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C - the sudden need to urinate with difficulty deferring and potential associated incontinence
What is pelvic girdle pain? When is the condition most common?
Pelvic girdle pain (PGP), which is also sometimes known as symphysis pubis dysfunction (SPD), is a condition that causes discomfort or pain in the joints at the front or back of the pelvis. The condition is most common in women during pregnancy
What are the symptoms of pelvic girdle pain?
* Low back or hip pain when bending over * Pain in legs, lower back or hips while walking, or climbing stairs * Low back or hip pain while sitting, or standing on one leg * Low back or hip pain turning over in bed * Low back or hip pain moving your legs apart * Back or hip pain during sex.
Pelvic girdle pain typically causes a pain around the lower back - can affect the front also What are risk factors for the condition? (5 factors)
Those who have had PGP in a previous pregnancy and Those who are prone to lower back pain Also Those with poor sitting posture at work or at computers Those who have a BMI greater than 30 Those who have a hard labour job
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Risk factors (5) Pelvic girdle pain in a previous pregnancy Those who are prone to lower back pain Hard labour job Poor posture while sitting Those with an increased BMI D - Time since last pregnancy is not a risk factor for PGP
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D - To oxygenate the foetal venous return using the right ventricle So the blood from the right ventricle that is pumped into the pulmonary trunk where the ductus arteriosus will drain the blood from here into the arch of the aorta to become oxygenated by the placneta
WHat is the valve that directs oxygenated blood through the foramen ovale to be pumped into the aorta that will reach the brain? All the other deoxygenated blood travels to the umbilical artery and to the placenta
This is the Eustachian valve
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D - It is mostly made by the foetal lung The foetus only begins to swallow amnitoic fluid in the late third trimester
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D - Resuscitation of term infants should commence in 100% oxygen - this is wrong it should commence in air
What oxygen concentration should be used initially for resuscitation of preterm infants?
Initially a low oxygen concentration of 21-30% should be used in preterm infants despite effective ventilation, oxygenation (ideally guided by oximetry) remains unacceptable, use of a higher concentration of oxygen should be considered.