Visual System Physiology Flashcards
Photoreceptor cells are connected to?
Bipolar cells
Bipolar cells are connected to?
Ganglion cells
What cell’s axons form the optic nerve?
Ganglion cells
Where does the amount of rods peak?
20 degrees off center
Where does the amount of cones peak?
At the center - fovea
Cones are used for?
Color detection and visual acuity
Rods are used for?
Light detection and have a high sensitivity
Darkness does what to the photoreceptor cells?
Depolarizes
If a photoreceptor is depolarized, what will it release to the bipolar cell?
LOTS of glutamate
If LOTS of glutamate is released to a bipolar cell, what receptor will it bind?
mGLUR6
What is the action of mGLUR6?
It closes cGMP-gated sodium channels = bipolar cell is inhibited!
Light does what to the photoreceptor cells?
Hyperpolarizes
If a photoreceptor is hyperpolarized, what will it release to the bipolar cell?
LOW amounts of glutamate
If LOW amounts of glutamate are released to a bipolar cell, what happens?
The bipolar cell will spontaneously depolarize
If a bipolar cell depolarizes, it will release ____ to the ganglion cell and _____ it
Glutamate
Depolarize
What neurotransmitter do ganglion cells release?
Glutamate
What type of glutamate receptor does the ganglion cell have?
Normal - NMDA or non-NMDA that work to excite the cell with glutamate
What is the rate of glutamate release from photoreceptor cells?
Constant - only the amounts are changeable
What are some direct targets of the retina?
LGN Superior colliculus Pretectum Hypothalamus Accessory optic nuclei
Converge eyes to a point, controls focus, detects movement, maps position of objects around you
Lateral Geniculate Nucleus