Vasoactive Drugs - Phenylephrine (#1 pressor given) Flashcards
What is the typical dose range for Phenylephrine when administered as an IV push?
A) 10-20 mcg
B) 20-50 mcg
C) 50-100 mcg
D) 100-200 mcg
E) 200-300 mcg
C) 50-100 mcg
What is the concentration of premade Phenylephrine in a standard stick?
A) 10 mcg/mL
B) 20 mcg/mL
C) 50 mcg/mL
D) 100 mcg/mL
E) 200 mcg/mL
D) 100 mcg/mL
100 mcg/mL premade stick;
What is the dose range for Phenylephrine when administered as a continuous IV infusion (gtt)?
A) 5-10 mcg/min
B) 10-20 mcg/min
C) 20-50 mcg/min
D) 50-100 mcg/min
E) 100-200 mcg/min
C) 20-50 mcg/min
What is the concentration of Phenylephrine in a solution prepared for continuous IV infusion (gtt) when using 10 mg in 250 mL?
A) 10 mcg/mL
B) 20 mcg/mL
C) 30 mcg/mL
D) 40 mcg/mL
E) 50 mcg/mL
D) 40 mcg/mL
What is the onset time for Phenylephrine when administered?
A) 1-2 minutes
B) 5-10 minutes
C) 10-15 minutes
D) 20-30 minutes
E) 30-60 minutes
C) 10-15 minutes
What is the mechanism of action (MOA) of Phenylephrine?
A) Beta-1 adrenergic agonist
B) Beta-2 adrenergic agonist
C) Direct sympathomimetic (alpha-1 adrenergic)
D) Indirect sympathomimetic (release of norepinephrine)
E) Calcium channel blocker
C) Direct sympathomimetic (alpha-1 adrenergic)
What is the half-life of Phenylephrine?
A) 0.5 hours
B) 1 hour
C) 2.5 hours
D) 5 hours
E) 10 hours
C) 2.5 hours
What is the duration of action for Phenylephrine?
A) 5 minutes
B) 15 minutes
C) 30 minutes
D) 1 hour
E) 2 hours
B) 15 minutes
How is Phenylephrine primarily metabolized?
A) In the liver
B) In the kidneys
C) In the intestinal wall
D) In the lungs
E) In the plasma
C) In the intestinal wall
Elimination: Metabolized in intestinal wall and minimally in liver
Where is Phenylephrine primarily excreted?
A) Feces
B) Saliva
C) Urine
D) Sweat
E) Bile
C) Urine
Action:
alpha +++
beta1 zero
beta2 +
CO -
HR -
Dysrhythmias N/A
When is Phenylephrine typically administered in the context of a cesarean section?
A) Before the spinal block is placed
B) Routinely after the spinal block placement
C) During the delivery of the baby
D) After the delivery and suturing is completed
E) Before induction of general anesthesia
B) Routinely after the spinal block placement
Which of the following is a contraindication for the use of Phenylephrine?
A) Pregnancy
B) Heart failure
C) Chronic kidney disease
D) Mild hypotension
E) Allergic reactions
B) Heart failure
In which of the following conditions should Phenylephrine be avoided?
A) Hypertension
B) Cardiogenic shock
C) Diabetes mellitus
D) Acute bronchitis
E) Hypoglycemia
B) Cardiogenic shock
What precaution should be taken when administering Phenylephrine, particularly in younger patients?
A) Monitor for reflex tachycardia
B) Watch for reflex bradycardia
C) Observe for hyperglycemia
D) Check for respiratory depression
E) Assess for skin rash
B) Watch for reflex bradycardia
Precautions: Watch for reflex bradycardia especially in younger pts (more vagal tone)!!
