Downers - Cardizem

Question 1

What is the dose range for Cardizem when administered as an intravenous (IV) infusion?
(Select all that apply)

A. 1-10 mg load
B. 2.5-25 mg load
C. 50-100 mg load
D. 25-50 mg load

Answer 1

B. 2.5-25 mg load

Question 2

What is the concentration of Cardizem when prepared for IV infusion?
(Select all that apply)

A. 100 mg in 100 mL
B. 50 mg in 50 mL
C. 1 mg/mL
D. 10 mg in 10 mL

Answer 2

A. 100 mg in 100 mL =
C. 1 mg/mL

Question 3

Which of the following accurately describes Cardizem’s effects as a calcium channel blocker?
(Select all that apply)

A. Cardizem is a benzothiazepine CCB.
B. Cardizem dilates peripheral arterioles more than coronary arterioles.
C. Cardizem prolongs AV nodal conduction.
D. Cardizem primarily acts on the veins to reduce preload.

Answer: A, C

Answer 3

A. Cardizem is a benzothiazepine CCB.
C. Cardizem prolongs AV nodal conduction.

Question 4

Cardizem’s MOA includes which of the following?
(Select all that apply)

A. Prolonging AV nodal conduction
B. Dilating coronary arterioles more than peripheral arterioles
C. Inhibiting beta-adrenergic receptors
D. Dilating peripheral arterioles more than coronary arterioles

Answer 4

A. Prolonging AV nodal conduction
B. Dilating coronary arterioles more than peripheral arterioles

Question 5

What is the onset time for Cardizem when administered intravenously?
(Select all that apply)

A. 1-2 minutes
B. 2-3 minutes
C. 5-10 minutes
D. 15-20 minutes

Answer 5

B. 2-3 minutes

Question 6

What is the duration of Cardizem’s effect with an intravenous infusion?
(Select all that apply)

A. 1-2 hours
B. 2-3 hours
C. 1-10 hours
D. 10-12 hours

Answer 6

C. 1-10 hours

Question 6

What is the half-life of Cardizem?
(Select all that apply)

A. 2 hours
B. 4 hours
C. 6 hours
D. 8 hours

Answer 6

B. 4 hours

Question 7

How is Cardizem eliminated from the body?
(Select all that apply)

A. Renal excretion
B. Hepatic metabolism
C. Biliary excretion
D. Respiratory excretion

Answer 7

B. Hepatic metabolism

Question 8

Which of the following conditions can Cardizem be used to treat?
(Select all that apply)

A. Supraventricular tachycardia (SVT)
B. Atrial fibrillation/flutter
C. Hypertension
D. Angina

Answer 8

A. Supraventricular tachycardia (SVT)
B. Atrial fibrillation/flutter
D. Angina

Question 9

Which of the following conditions is a contraindication for using Cardizem?
(Select all that apply)

A. Wolff-Parkinson-White (WPW) syndrome with accessory pathways
B. Atrial fibrillation
C. Stable angina
D. Supraventricular tachycardia (SVT)

Answer 9

A. Wolff-Parkinson-White (WPW) syndrome with accessory pathways

C/I: WBW accessory pathway (doesn’t work)

Question 10

Which of the following precautions should be taken when administering Cardizem?
(Select all that apply)

A. Avoid using Cardizem infusion for more than 24 hours
B. Use Cardizem infusion for more than 24 hours if needed
C. Exercise caution when used with beta-blockers
D. Caution with wide QRS complexes of unknown etiology and short PR intervals

Answer 10

A. Avoid using Cardizem infusion for more than 24 hours
C. Exercise caution when used with beta-blockers
D. Caution with wide QRS complexes of unknown etiology and short PR intervals

Question 11

Which of the following are side effects of Cardizem?
(Select all that apply)

A. Little effect on normal heart rates
B. Minimal inotropic effect
C. Rare elevation of liver function tests (LFTs)
D. Increased heart rate

Answer 11

A. Little effect on normal heart rates
B. Minimal inotropic effect
C. Rare elevation of liver function tests (LFTs)