Antiemetics - Dexamethasone (Decadron) Flashcards
What is the recommended dose range of Dexamethasone (Decadron) for adult patients experiencing post-operative nausea and vomiting (PONV)?
A) 2-4 mg
B) 4-8 mg
C) 8-12 mg
D) 10-15 mg
B) 4-8 mg
For the management of PONV in pediatric patients, which of the following are correct dose ranges for Dexamethasone (Decadron)? (Select 2)
A) 0.1 mg/kg
B) 0.25 mg/kg
C) 0.5 mg/kg
D) Maximum of 4 mg
B) 0.25 mg/kg
D) Maximum of 4 mg
Which dose of Dexamethasone (Decadron) is commonly used for managing cranies/backs; cerebral or spinal edema in patients?
A) 4 mg
B) 8 mg
C) 10 mg
D) 20 mg
C) 10 mg
Dexamethasone (Decadron) is used at which of the following doses for pediatric ENT procedures?
A) 4-8 mg
B) 8-12 mg
C) 12-16 mg
D) 16-20 mg
B) 8-12 mg
For the treatment of shock, what is the maximum dose of Dexamethasone (Decadron) that can be administered?
A) 10 mg
B) 20 mg
C) 30 mg
D) 40 mg
D) up to 40 mg
Which of the following doses are appropriate for the use of Dexamethasone (Decadron) in the management of airway edema during difficult intubations?
A) 2-4 mg
B) 4-12 mg
C) 8-12 mg
D) 12-16 mg
B) 4-12mg
Airway Edema: 4-12mg (ENT or difficult intubations)
How does a 4 mg dose of Dexamethasone (Decadron) compare to Droperidol in terms of dosage equivalency?
A) 4 mg Dexamethasone = 0.625 mg Droperidol
B) 4 mg Dexamethasone = 1 mg Droperidol
C) 4 mg Dexamethasone = 2 mg Droperidol
D) 4 mg Dexamethasone = 5 mg Droperidol
A) 4 mg Dexamethasone = 0.625 mg Droperidol
4mg Decadron
= 4mg Ondansetron (Zofran)
= 0.625 mg Droperidol
How does Dexamethasone (Decadron) control inflammation at the cellular level?
A) By inhibiting serotonin release
B) By controlling the rate of inflammatory modulator protein synthesis
C) By blocking calcium channels
D) By enhancing the release of neurotransmitters
Answer: B) By controlling the rate of inflammatory modulator protein synthesis
MOA: glucocorticoid steroid; controls rate of inflammatory modulator protein synthesis, suppresses migration of inflammatory cells, reverse capillary permeability
What is the concentration of Dexamethasone (Decadron) provided in the solution?
A) 2 mg/mL
B) 4 mg/mL
C) 6 mg/mL
D) 8 mg/mL
B) 4 mg/mL
Which statement best describes how Dexamethasone (Decadron) influences inflammatory response?
A) It enhances the migration of inflammatory cells to the site of injury.
B) It suppresses the migration of inflammatory cells and reverses capillary permeability.
C) It increases the synthesis of pro-inflammatory proteins.
D) It directly blocks the synthesis of neurotransmitters involved in inflammation.
Answer: B) It suppresses the migration of inflammatory cells and reverses capillary permeability.
What is the onset time of Dexamethasone (Decadron)?
A) 30 minutes
B) 1 hour
C) 2 hours
D) 4 hours
C) 2 hours
Tx Wes Reference:
10-30 min
When should Dexamethasone (Decadron) be administered during a surgical procedure?
A) Before induction
B) During induction
C) After induction
D) At the end of the procedure
Answer: C) After induction
What is the duration of efficacy for Dexamethasone (Decadron)?
A) 6 hours
B) 12 hours
C) 24 hours
D) 48 hours
Answer: C) 24 hours
Tx Wes Reference:
2-10 hr
1.
How is Dexamethasone (Decadron) primarily metabolized and excreted from the body?
A) Hepatic metabolism and renal excretion
B) Renal metabolism and fecal excretion
C) Hepatic metabolism and fecal excretion
D) Renal metabolism and urinary excretion
Answer: A) Hepatic metabolism and renal excretion
What is the elimination half-life of Dexamethasone (Decadron)?
A) 1 hour
B) 2 hours
C) 3 hours
D) 4 hours
Answer: C) 3 hours