Analgesics/NSAIDS - Ketorolac (Toradol) Flashcards
What is the recommended IV dose of Ketorolac (Toradol) for an adult patient?
A) 10 mg IV Q6H
B) 15 mg IV Q6H
C) 20 mg IV Q6H
D) 30 mg IV Q6H
B) 15 mg IV Q6H
TxWes Reference:
15-30mg q6h
max 60-120mg qd
What is the recommended IV dose of Ketorolac (Toradol) for a pediatric patient?
A) 0.25 mg/kg IV Q6H
B) 0.5 mg/kg IV Q6H
C) 1 mg/kg IV Q6H
D) 2 mg/kg IV Q6H
B) 0.5 mg/kg IV Q6H
Given the concentration of Ketorolac (Toradol) is 30 mg/mL, how many milliliters are needed to administer a 15 mg dose?
A) 0.25 mL
B) 0.5 mL
C) 1 mL
D) 1.5 mL
Answer: B) 0.5 mL
Concentration: 30mg/mL
What is the primary mechanism of action of Ketorolac (Toradol)?
A) Inhibition of dopamine receptors
B) Selective inhibition of COX-2 enzyme
C) Non-selective inhibition of COX-1 and COX-2 enzymes
D) Inhibition of serotonin reuptake
C) Non-selective inhibition of COX-1 and COX-2 enzymes
MOA: NSAID; Non-selective COX inhibitor; Anti-inflammatory, antipyretic and analgesic effects is the inhibition of prostaglandin synthesis by competitive blocking of the enzyme cyclooxygenase (COX).
What is the typical onset time for Ketorolac (Toradol) when administered?
A) 1 minute
B) 5 minutes
C) 10 minutes
D) 30 minutes
Answer: C) 10 minutes
When does Ketorolac (Toradol) usually reach its peak effect after administration?
A) 30 minutes
B) 1 hour
C) 2 hours
D) 4 hours
Answer: C) 2 hours
What is the approximate half-life of Ketorolac (Toradol)?
A) 1-2 hours
B) 2-3 hours
C) 4.5 hours
D) 6.5 hours
Answer: C) 4.5 hours
How is Ketorolac (Toradol) primarily metabolized and eliminated from the body?
A) Hepatic metabolism; excreted in bile
B) Hepatic metabolism; excreted renally
C) Renal metabolism; excreted in urine
D) Renal metabolism; excreted in feces
Answer: B) Hepatic metabolism; excreted renally
How does Ketorolac (Toradol) function as an adjunct to opioid administration for severe pain?
A) By enhancing the respiratory depression effects of opioids
B) By providing additional analgesic effects without causing respiratory depression
C) By replacing opioids entirely in pain management
D) By increasing the dose of opioids needed
Answer: B) By providing additional analgesic effects without causing respiratory depression
Action: Useful adjunct to parenteral/epidural opioid admin for severe pain; analgesic>anti-inflammatory; does not cause resp depression;
In terms of pain relief, how does Ketorolac (Toradol) compare to morphine?
A) Less effective than 10 mg of morphine
B) Equally effective as 10 mg of morphine
C) More effective than 10 mg of morphine
D) Not used for comparison with morphine
Answer: B) Equally effective as 10 mg of morphine
Before administering Ketorolac (Toradol) during a C-section or abdominal surgery, what is a recommended step?
A) Administer the drug immediately without consultation
B) Consult the surgeon before giving Ketorolac (Toradol)
C) Increase the opioid dose
D) Avoid using any adjuncts
Answer: B) Consult the surgeon before giving Ketorolac (Toradol)
Which of the following is a contraindication for using Ketorolac (Toradol)?
A) Hypertension
B) Allergy to NSAIDs
C) Diabetes
D) Hypothyroidism
Answer: B) Allergy to NSAIDs
Ketorolac (Toradol) should be avoided in patients with which of the following gastrointestinal conditions?
A) Constipation
B) Gastroesophageal reflux disease (GERD)
C) Active peptic ulcer or bleeding disorder
D) Irritable bowel syndrome (IBS)
Answer: C) Active peptic ulcer or bleeding disorder
Which patient group is Ketorolac (Toradol) contraindicated?
A) Patients with diabetes
B) Patients with asthma or reactive airways
C) Patients with seasonal allergies
D) Patients with minor skin conditions
B) Patients with asthma or reactive airways
In which patient population should the dose of Ketorolac (Toradol) be reduced by 50% due to potential risks?
A) Pediatric patients
B) Pregnant patients
C) Elderly patients or those with renal insufficiency
D) Patients with diabetes
Answer: C) Elderly patients or those with renal insufficiency
