Vasculitis Flashcards
Def = Granulomatosis vasculitis involving branches of the carotid a.
Temporal/Giant cell arteritis
Bx = segmental intimal fibrosis w/ giant cells
Temporal/Giant cell arteritis
Def = Granulomatous vasculitis of aortic arch at branch points
Takayasu arteritis
MC demographic for Takayasu arteritis
Asian W < 50
Sx’s = Weak/absent UE pulses
Takayasu arteritis
Which lab value will be elevated in Takayasu arteritis
ESR
Def = Necrotizing vasculitis of many organs, SPARING lungs
PAN
MC demographic for PAN
Young adults w/ HTN
Bx = transmural inflammation w/ fibrinoid necrosis
PAN
What is seen on imaging in PAN
‘string-of-beads’
PAN assc w/…
HBV
Sx’s = erythematous rash on palms/soles w/ enlarged cervical LN’s in Asian child < 5 yo
Kawasaki disease
Tx of Kawasaki disease =
ASA, IVIg
Def = Necrotizing vasculitis involving digits in young, heavy smokers
Buerger disease
Def = Necrotizing granulomatous vasculitis of nasopharynx, lungs, and kidneys
Wegener Granulomatosis
Bx = large necrotizing granulomas w/ adjacent necrotizing vasculitis
Wegener Granulomatosis
c-ANCA +
Wegener Granulomatosis
Sx’s = sinusitis, nasopharyngeal ulceration, hemoptysis (b/l lung infiltrates), hematuria in middle-aged male
Wegener Granulomatosis
Pneumonic for Wegener’s Granulomatosis
weCner –> c-ANCA, Cyclophosphamide, C-shaped organ involvement
Def = Necrotizing vasculitis of lungs and kidneys
Microscopic Polyangiitis
p-ANCA +
Microscopic Polyangiitis, Churg-Straus syndrome
Tx of Microscopic Polyangiitis
Cyclophosphamide
Def = Necrotizing granulomatous inflammation w/ eosinophilia involving lungs and heart
Churg-Strauss syndrome
Def = IgA immune complex deposition in kidneys following URI in kids
Henoch-Schonlein purpura
