Repro - Ovaries Flashcards

1
Q

Function of Estradiol

A

Stimulate LH surge –> ovulation

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2
Q

What is Struma Ovarii

A

Teratoma composed of thyroid tissue

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3
Q

Function of LH

A

Stimulate theca cells –> produce androgens

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4
Q

Fibroma + Pleural effusion + Ascites =

A

Meigs syndrome

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5
Q

Def = tumor of fetal tissue from 2-3 embryonic layers

A

Cystic teratoma

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6
Q

Def = Single cyst w/ simple, flat lining in premenopausal women

A

Cystadenoma (benign)

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7
Q

Mucus in peritoneum d/t mucinous tumor of the appendix =

A

Pseudomyxoma peritonei

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8
Q

Def = complex cysts w/ thick, shaggy lining in postmenopausal women

A

Cystadenocarcinoma (malignant)

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9
Q

What is elevated in endodermal sinus tumors

A

AFP

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10
Q

Def = ovarian tumor of cytotrophoblasts and syncytiotrophoblasts

A

Choriocarcinoma

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11
Q

Def = ovarian tumor composed of endometrial-like glands

A

Endometrioid epithelial tumor

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12
Q

Def = ovarian tumor assc w/ hirsutism and virilization d/t androgen production

A

Sertoli-leydig cell tumor

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13
Q

What indicates malignancy in teratomas

A

Presence of immature tissue - typically neural ectoderm

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14
Q

Def = ovarian tumor of benign fibroblasts

A

Fibroma

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15
Q

Def = ovarian tumor producing excess E –> endodermal hyperplasia in post-meno women or precocious puberty in young women

A

Granulosa-theca cell tumor

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16
Q

What is elevated in choriocarcinomas

A

ß-hCG

17
Q

What will be seen on Bx of Sertoli-leydig cell tumors

A

Reinke crystals

18
Q

How is Krukenbarg tumor distinguished from primary mucinous carcinoma

A

Krukenberg = b/l involvement

19
Q

Def = ovarian tumor composed of bladder-like epithelium

A

Brenner epithelial tumor

20
Q

Function of FSH

A

Stimulate granulosa cells –> androgen to E

21
Q

Def = ovarian tumor mimicking yolk sac in children

A

Endodermal sinus tumor

22
Q

Def = ovarian tumor of large cells w/ clear cytoplasm and central nuclei w/ LDH elevation

A

Dysgerminoma

23
Q

Gene mutation increasing the risk of ovarian carcinoma

A

BRCA1

24
Q

What is the hormone imbalance causing PCOS

A

LH:FSH > 2

25
Q

Bx of endodermal sinus tumors

A

Schiller-Duval bodies (glomerulus-like structures)

26
Q

How does PCOS cause infertility

A

Excess LH –> Excess androgen –> Conversion to E in adipose tissue –> Inhibition of FSH