Anti-HIV Drugs Flashcards
1
Q
MOA of NRTI’s
A
Nucleoside reverse transcriptase Inhibitors –> DNA termination
2
Q
MOA of NNRTI’s
A
Non-Nucleoside reverse transcriptase inhibitors –> DNA termination
3
Q
MOA of Protease inhibitors
A
Prevent maturation of new virus by inhibiting cleavage of polypeptide products
4
Q
MOA of Integrase inhibitors
A
Inhibit HIV genome integration by binding HIV integrase
5
Q
MOA of Maraviroc
A
Inhibits viral interaction w/ gp120 via binding CCR5 on T cell
6
Q
MOA of Enfuvirtide
A
Inhibits viral entry into cell via gp41 binding
7
Q
Protease inhibitor drugs =
A
‘-navir’
8
Q
Integrase inhibitor drugs =
A
‘-tegravir’
9
Q
NNRTI drugs =
A
Delavirdine, Efavirenz, Nevirapine
