Review 4 Flashcards
How do conjugate vaccines affect lymphocytes
Increase B and T cell response
Cause of hyperacute transplant rejection =
Host Abs attack donor tissue
Cause of acute transplant rejection =
Donor Ags activate immune response
Cause of chronic transplant rejection =
Chronic low-grade host immune response
How do virus infected cells cause cell death
Activation of IFN’s –> inhibition of protein synthesis by infected cells
How is Nitroblue Tetrazolium test assc w/ Chronic Granulomatous Disease
If neutrophils don’t turn blue = CGD –> MC d/t NADPH oxidase mutation –> free radical destruction
Anaphylaxis is d/t release of…
Histamine and Tryptase
Mutation assc w/ SCID =
Adenosine deaminase
Type of rash assc w/ 2˚ syphilis =
Maculopapular/Pustular rash NOT vesicular (Reactive arthritis)
What is known in a Cohort study
Exposure
What is known in a Case-control study
Disease outcome
Construction + MS∆ + Constipation + Microcytic anemia =
Pb intoxication
What decreases the risk of Sickle cell crisis in SCD
Increased HbA
RBC’s lacking central pallor =
Hereditary spherocytosis
What is the cause of MetHgb
Drug exposure
Major SE of Vincristine =
Peripheral neuropathy
What LN’s will the inferior rectal LN’s drain into
Inguinal LN’s
What does LMWH do to ATIII
Binds and inhibits ATIII
Diffuse, medium-sized lymphocytes w/ increased proliferative index (Ki-67) =
Burkitt lymphoma
Oculocutaneous albinism + Peripheral neuropathy + immunodeficiency =
Chediak Higashi
Wiskott-Aldrich =
B/T-cell disorder w/ thrombocytopenia –> increased risk of pyogenic infetions
What vitamin do SCD pts need
Folate
What are the afferent and efferent CN’s in the cough reflex
Afferent = CN X Efferent = CN X
What are the afferent and efferent CN’s in the gag reflex
Afferent = CN IX Efferent = CN X
