Review 4

Question 1

How do conjugate vaccines affect lymphocytes

Answer 1

Increase B and T cell response

Question 2

Cause of hyperacute transplant rejection =

Answer 2

Host Abs attack donor tissue

Question 3

Cause of acute transplant rejection =

Answer 3

Donor Ags activate immune response

Question 4

Cause of chronic transplant rejection =

Answer 4

Chronic low-grade host immune response

Question 5

How do virus infected cells cause cell death

Answer 5

Activation of IFN’s –> inhibition of protein synthesis by infected cells

Question 6

How is Nitroblue Tetrazolium test assc w/ Chronic Granulomatous Disease

Answer 6

If neutrophils don’t turn blue = CGD –> MC d/t NADPH oxidase mutation –> free radical destruction

Question 7

Anaphylaxis is d/t release of…

Answer 7

Histamine and Tryptase

Question 8

Mutation assc w/ SCID =

Answer 8

Adenosine deaminase

Question 9

Type of rash assc w/ 2˚ syphilis =

Answer 9

Maculopapular/Pustular rash NOT vesicular (Reactive arthritis)

Question 10

What is known in a Cohort study

Answer 10

Exposure

Question 11

What is known in a Case-control study

Answer 11

Disease outcome

Question 12

Construction + MS∆ + Constipation + Microcytic anemia =

Answer 12

Pb intoxication

Question 13

What decreases the risk of Sickle cell crisis in SCD

Answer 13

Increased HbA

Question 14

RBC’s lacking central pallor =

Answer 14

Hereditary spherocytosis

Question 15

What is the cause of MetHgb

Answer 15

Drug exposure

Question 16

Major SE of Vincristine =

Answer 16

Peripheral neuropathy

Question 17

What LN’s will the inferior rectal LN’s drain into

Answer 17

Inguinal LN’s

Question 18

What does LMWH do to ATIII

Answer 18

Binds and inhibits ATIII

Question 19

Diffuse, medium-sized lymphocytes w/ increased proliferative index (Ki-67) =

Answer 19

Burkitt lymphoma

Question 20

Oculocutaneous albinism + Peripheral neuropathy + immunodeficiency =

Answer 20

Chediak Higashi

Question 21

Wiskott-Aldrich =

Answer 21

B/T-cell disorder w/ thrombocytopenia –> increased risk of pyogenic infetions

Question 22

What vitamin do SCD pts need

Answer 22

Folate

Question 23

What are the afferent and efferent CN’s in the cough reflex

Answer 23

Afferent = CN X
Efferent = CN X

Question 24

What are the afferent and efferent CN’s in the gag reflex

Answer 24

Afferent = CN IX
Efferent = CN X

Question 25

What is the effect of a pineal gland mass

Answer 25

Cerebral aqueduct stenosis –> increased ICP –> Papilladema, HA, V

Question 26

Are the aortic branches in the hip retro or intraperitoneal

Answer 26

Retroperitoneal

Question 27

If a pt can’t look down, which nerve is injured

Answer 27

Trochlear