Kidney Flashcards
Def = thick glomerular BM d/t subePithelial immune complex deposition –> ‘spike and dome’ appearance
Membranous nephropathy
Def = thinning/splitting of glomerular BM d/t type 4 collagen defect
Alport syndrome
Where does amyloid deposit in the kidney
Mesangium
Demographic for M∆D =
Kids
Def = normal looking glomeruli w/ effacement of foot processes and selective proteinuria
Minimal Change Disease
Def = effacement of foot processes and destruction of parts of some glomeruli
FSGS
Beckwith-Wiedmann syndrome =
Wilms Tumor + Neonatal hypoglycemia + Muscular hemihypertrophy + Organomegaly
Def = IgA complex deposition in mesangium of glomeruli post-mucosal infection in childhood
IgA Nephropathy (Berger disease)
What kind of casts are seen in urine in chronic pyelonephritis
Waxy casts
Minimal change disease is assc w/
HL
Def = hypercellular, inflamed glomeruli w/ subePithelial humps after infection w/ Group A Strep
PSGN
Def = thick glomerular BM d/t subeNDothelial immune complex deposition –> ‘tram-track’ appearance
MPGN
Def = large, u/l flank mass w/ hematuria and HTN in kids
Wilms tumor
What drugs slow progression of DM glomerular disease
ACEi’s
Sx’s of Alport syndrome =
Hematuria, Hearing loss, Ocular disturbances
