Urinary System Part A (Final Exam) Flashcards

1
Q

kidney regulatory functions

What are the five regulatory functions of the kidney?

A

1.) Blood volume
2.) Blood pressure
3.) Blood pH
4.) Blood ionic composition
5.) Blood glucose level

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2
Q

organs that work w/ urinary system

What are the 3 other organs that work with the urinary system?

A

1.) ureter
2.) urinary bladder
3.) urethra

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3
Q

organs that work w/ urinary system

What is the function of the ureter?

A

to transport urine from the kidneys to the bladder

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4
Q

organs that work w/ urinary system

what is the function of the urinary bladder?

A

to serve as a temporary storage reservoir for urine

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5
Q

organs that work w/ urinary system

What is the function of the urethra?

A

to move urine out of the body

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6
Q

internal kidney

What are the three regions of the internal kidney?

A

The three regions of the internal kidney are the

1.) renal cortex
2.) renal medulla
3.) renal pelvis

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7
Q

internal kidney

What is the renal cortex?

A

The renal cortex is the granular appearing superficial region of the kidney.

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8
Q

internal kidney

Where is the renal medulla located?

A

The renal medulla is located deep within the kidney.

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9
Q

internal kidney

What are the structures found in the renal medulla?

A

The renal medulla contains cone-shaped renal pyramids that are separated by renal columns.

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10
Q

internal kidney

What is the renal pelvis?

A

The renal pelvis is a funnel-shaped tube that is continuous with the ureter.

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11
Q

internal kidney

What are the two parts of the renal pelvis?

A

The two parts of the renal pelvis are the
1.) minor calyces
2.) major calyces

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12
Q

internal kidney

What is the function of the minor calyces?

A

The minor calyces are cup-shaped areas that collect urine.

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13
Q

internal kidney

What is the function of the major calyces?

A

The major calyces collect urine from the minor calyces and empty the urine into the renal pelvis.

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14
Q

urine pathflow inside kidney

What is the path of urine flow inside the kidney? (6)

A

Nephron –> Renal Pyramid —> Minor Calyx –> Major Calyx —> Renal Pelvis –> Ureter

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15
Q

nephrons

What are nephrons?

A

structural and functional units of the kidneys that make urine

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16
Q

part of nephrons & functions

What are the 2 parts of the nephrons?

A

1.) renal corpuscle
2.) renal tubule

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17
Q

part of nephrons & functions

What are the 2 parts of the renal corpuscle and their functions?

A

The two parts of the renal corpuscle are the

1.) glomerulus (blood vessels)
- to help with efficient filtrate formation

2.) glomerular capsule
- has filtration slits to help filter

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18
Q

part of nephrons & functions

What are the 3 parts of the renal tubule and their functions?

A

1.) proximal convoluted tubule
- reabsorption and secretion

2.) nephron loop
- u-shaped structure with two limbs (descending and ascending)

3.) distal convoluted tubule
- more in secretion than reabsorption, and it drains into the collecting duct

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19
Q

part of nephrons & functions

Do all three parts of the renal tubule hook up to the collecting duct?

A

Yes, all three parts of the renal tubule (proximal convoluted tube, nephron loop, distal convoluted tubule) hook up to the collecting duct.

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20
Q

classes of nephrons & capillary beds

What are the 2 classes of nephrons?

A

1.) cortical nephrons
2.) juxtamedullary nephrons

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21
Q

classes of nephrons & capillary beds

What supplies the cortical nephrons?

A

The cortical nephrons are supplied by peritubular capillaries.

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22
Q

classes of nephrons & capillary beds

What supplies the juxtamedullary nephrons?

A

The juxtamedullary nephrons are supplied by juxtamedullary capillaries.

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23
Q

process of urine formation/adjustment of blood composition

What are the 3 processes involved in urine formation/adjustment of blood composition?

A

The 3 processes are

1.) glomerular filtration
2.) tubular reabsorption
3.) tubular secretion

24
Q

process of urine formation/adjustment of blood composition

What happens during glomerular filtration?

A

Water and solutes in blood plasma move across glomerular capillary walls into glomerular capsule and renal tubule.

25
Q

process of urine formation/adjustment of blood composition

What is tubular reabsorption?

A

Tubular reabsorption is the process where filtrate goes from the renal tubule back into the blood, such as in the case of dehydration.

nephron to blood

26
Q

process of urine formation/adjustment of blood composition

What is tubular secretion?

A

Tubular secretion is the opposite of tubular reabsorption, where substances such as water, ions, and waste are taken from the blood and deposited into the renal tubule.

blood to nephron

27
Q

glomerular filtration

What is glomerular filtration?

A

Glomerular filtration is the process by which fluid and solutes are forced through the filtration membrane into the glomerular capsule.

28
Q

glomerular filtration

Is glomerular filtration a passive or active process?

A

Glomerular filtration is a passive process that does not require any energy

29
Q

glomerular filtration

What forces fluid and solutes through the filtration membrane in glomerular filtration?

A

Pressure is the force that pushes fluid and solutes through the filtration membrane into the glomerular capsule.

30
Q

filtration membrane

What is the filtration membrane?

A

The filtration membrane is the membrane between the blood and inside of the glomerular capsule.

31
Q

filtration membrane

What does the filtration membrane allow?

A

The filtration membrane allows filtration of water and small solutes.

32
Q

filtration membrane

What does the filtration membrane prevent from being filtered?

A

The filtration membrane prevents filtration of plasma proteins, blood cells, and platelets.

33
Q

filtration membrane layers

What are the three layers of the filtration membrane?

A

The three layers of the filtration membrane are

1.) glomerular endothelial cells
2.) basal lamina
3.) filtration slits

34
Q

filtration membrane layers

What is the function of glomerular endothelial cells in the filtration membrane?

A

Glomerular endothelial cells prevent filtration like a strainer.

35
Q

filtration membrane layers

What is the function of basal lamina in the filtration membrane?

A

prevents filtration of larger proteins like antibodies

36
Q

filtration membrane layers

What is the function of filtration slits in the filtration membrane?

A

prevent filtration of medium sized proteins.

37
Q

pressures that affect filtration

What are the 2 types of pressures that affect filtration?

A

1.) promoting filtration
2.) pressure opposing filtration

38
Q

pressures that affect filtration

What is pressure promoting filtration?

A

the type of pressure that pushes fluids out of the blood vessels and into the surrounding tissues.

39
Q

pressures that affect filtration

What is glomerular blood hydrostatic pressure (GBHP)?

promoting or opposing?

A

Glomerular blood hydrostatic pressure (GBHP) is the pressure of blood in glomerular capillaries, which is

approximately 55 mm HG.

promoting pressure

40
Q

pressures that affect filtration

What is pressure opposing filtration?

A

type of pressure that opposes the movement of fluids out of the blood vessels and into the surrounding tissues

41
Q

pressures that affect filtration

What is capsular hydrostatic pressure (CHP)?

promoting or opposing?

A

Capsular hydrostatic pressure (CHP) is the pressure of filtrate already in the glomerular capsule, which is approximately 15 mm HG.

opposing

42
Q

pressures that affect filtration

What is blood colloid osmotic pressure (BCOP)?

promoting or opposing?

A

Blood colloid osmotic pressure (BCOP) is the pressure exerted by proteins in the blood that want to hold water in, which is approximately 30 mm HG.

opposing

43
Q

net filtration

What is net filtration?

A

\the sum of forces promoting filtration minus those opposing it

promoting filtration - pressure opposing = net filtration

In the case of 55 mm Hg promoting filtration and 45 mm Hg opposing filtration, the net filtration would be 10 mm Hg.

44
Q

glomerular filtration rate (GFR)

What is Glomerular Filtration Rate (GFR)?

A

the volume of filtration formed per minute by both kidneys

45
Q

glomerular filtration rate (GFR)

What are the 3 factors that affect Glomerular Filtration Rate (GFR)?

A

1.) net filtration pressure (NFP)
2.) total surface area available for filtration
3.) filtration membrane permeability

46
Q

glomerular filtration rate (GFR)

What is net filtration pressure (NFP)?

A

the pressure gradient that exists across the glomerular capillaries, which determines the direction and rate of fluid movement through the filtration membrane

47
Q

glomerular filtration rate (GFR)

What is the total surface area available for filtration in the kidneys?

A

The total surface area available for filtration in the kidneys is provided by the glomerular capillaries, which have a large surface area due to their branching structure and fenestrated endothelial cells.

48
Q

glomerular filtration rate (GFR)

What is the major factor that affects Glomerular Filtration Rate (GFR)?

A

The major factor that affects Glomerular Filtration Rate (GFR) is net filtration pressure (NFP).

49
Q

glomerular filtration rate (GFR)

What is filtration membrane permeability?

A

Filtration membrane permeability refers to the ability of the glomerular capillary endothelium, basement membrane, and podocyte foot processes to allow certain substances to pass through and be filtered out of the blood into the urinary space.

50
Q

mechanisms for regulating glomerular filtration rate (GFR)

What are the 3 mechanisms for regulating glomerular filtration rate (GFR)?

A

1.) renal autoregulation
2.) neural regulation
3.) hormonal regulation

51
Q

mechanisms for regulating glomerular filtration rate (GFR)

What are the two types of renal autoregulation?

A

The two types of renal autoregulation are the

1.) myogenic mechanism
2.) tubuloglomerular feedback mechanism

52
Q

mechanisms for regulating glomerular filtration rate (GFR)

How does the myogenic mechanism regulate GFR?

A

The myogenic mechanism regulates GFR by constricting the afferent arteriole in response to high blood pressure, which slows down GFR and protects fragile capillaries from high pressure.

53
Q

mechanisms for regulating glomerular filtration rate (GFR)

What is the benefit of the myogenic mechanism in regulating GFR?

A

The benefit of the myogenic mechanism is that it slows down GFR and protects fragile capillaries from high blood pressure.

54
Q

mechanisms for regulating glomerular filtration rate (GFR)

What is the tubuloglomerular feedback mechanism?

A

The tubuloglomerular feedback mechanism is a type of renal autoregulation that involves macula densa cells detecting changes in Na+ and Cl- concentration, which can lead to vasoconstriction of afferent arterioles and a decrease in GFR back to homeostasis.

55
Q

mechanisms for regulating glomerular filtration rate (GFR)

How does the neural regulation mechanism regulate GFR?

A

The neural regulation mechanism regulates GFR by using the sympathetic nervous system.

56
Q

mechanisms for regulating glomerular filtration rate (GFR)

What is the hormonal regulation mechanism for regulating GFR?

A

The hormonal regulation mechanism for regulating GFR uses the renin-angiotensin-aldosterone system.