Tumour pathology 1 Flashcards
tumour
abnormal growing mass of tissue.
growth uncoordinated with surrounding normal tissue.
will tumours continue to grow when their stimulus is removed
yes
cancer
a malignant tumour that is able to spread into adjacent tissues and metastasis and grow at other sites in the body.
metastasise
the spread of a malignant tumour (growth at a secondary sight).
classification of tumours
based on tissue of origin and whether it is benign or malignant.
nomenclature of epithelial tumours
based on type of epithelial tissue and whether the tumour is malignant or benign
adenoma
benign tumour of glandular tissue, eg. the mucosal of the small inestine, stomach or colon
adenocarcenoma
malignant tumour of glandular tissue
squamous papilloma
benign tumour in squamous epithelial tissue
squamous carcinoma
mailignant tumour of squamous epithelial tissue
osteoma
benign tumour of bone tissue
osteosarcoma
malignant tumour of bone tissue
lipoma
benign tumour of fat tissue
liposarcomma
malignant tumour of fat tissue
fibroma
benign tumour of fibrous connective tissue
firosarcomma
malignant tumour of fibrous connective tissue
leukaemia
malignant tumour of white blood cells
lymphoma
malignant tumour of lymphoid tissue
Naevus
benign tumour of melanocytes
melanoma
malignant tumour of melanocytes
astrocytoma
tumour of astrocytes in the CNS
schwannoma
tumour of the Schwann cells in the peripheral nervous system
teratomas
tumours of germ cells.
ovarian and testicular cancer malignancy comparison
ovarian teratomas are usually benign
testicular teratimas are usually malignant
Features of benign tumours
-non-invasive growth pattern
- usually encapsulated
-no evidence of invasion
-no metastases (secondary tumours)
-cells similar to normal so they are well differentiated
- have a function similar to normal tissue
rarely cause disease
features of malignant tumours
- invasive growth pattern
- no capsule of capsule breached
- cells abnormal so are poorly differentiated
- loss of normal function
- often evidence of spread of cancer
- frequently cause death