storing and using genetic information Flashcards
1
Q
structure of DNA
A
DNA is a polymer of nucleotide monomers arranged in a double helix shape which has two antiparallel strands.
2
Q
process of DNA replication
A
- DNA strands are ‘unzipped’
- DNA polymerase then acts on the strand, adding nucleotides from the 5’ to 3’ end of the DNA strand.
- this is continuous on the leading strand but is caried out in fragments on the lagging strand, these are then joined together by DNA ligase.
3
Q
process of transcription
A
- DNA is unzipped
- RNA polymerase works from 5’ to 3’ end of chain producing an RNA chain with a base sequence complementary to that on the DNA.
4
Q
post-transcriptional modification of RNA
A
Introns are removed form the primary RNA strand and the exons are spliced together to form the mature RNA strand.
5
Q
process of translation
A
- mRNA makes its way out of the nucleus to a ribosome
- tRNA molecules are bound to a specific amino acid
- they bring this amino acid to the ribosome. The tRMA contains an anticodon which is complementary to the codon on the mRNA. This allows amino acids to joined together in a polypeptide chain according to the sequence of bases on mRNA (and DNA)
6
Q
what is meant by DNA replication is semi-conservative?
A
after replication one strand is old and one is new