Toxicology Flashcards

1
Q

If a dog presents clinical signs after ingesting sugar-free medication or other substances, it’s best to assume

A

the presence of xylitol toxicity.

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2
Q

Several common household plants contain

A

insoluble calcium oxalate crystals.

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3
Q

The most hazardous form of antifreeze is

A

ethylene glycol.

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4
Q

In the case of ocular exposure, the eyes should be repeatedly flushed with

A

Lukewarm water

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5
Q

Corrosive substances that have been ingested should be diluted with

A

Milk

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6
Q

What’s the dosage of hydrogen peroxide used to induce vomiting in an animal?

A

1 tsp. (5 mL) per 5 lbs. of body weight

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7
Q

How is administering activated charcoal beneficial in a toxicosis case besides the adsorptive action?

A

It can prevent enterohepatic recirculation of metabolized toxicants.

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8
Q

What can be administered to dog that has ingested dough with raw yeast?

A

Cold water or ice cubes by mouth or through a stomach tube

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9
Q

Toxin

A

A natural biological substance that causes adverse effects in living beings

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10
Q

Toxicant

A

A synthetic substance that causes adverse effects in living beings

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10
Q

To dilute contents of a corrosive or irritant ingestion

A

1-3 ml/lb of water or milk

Exotic animals use juicy fruits or vegetables in place of milk.

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10
Q

Corrosive

A

A caustic substance that causes tissue damage

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11
Q

Neurotoxic

A

substance that alters the structure or function of the nervous system. More than 1,000 chemicals are known to have neurotoxic effects in animals.

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11
Q

Hepatotoxic

A

Chemical-driven liver damage -

One example- Agave

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12
Q

Nephrotoxic

A

Chemical-driven kidney damage

Some examples of substances: grapes/raisins

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13
Q

EMESIS – HYDROGEN PEROXIDE

A

For toxin ingestion. 1 tsp (5ml) per 5 lb of body weight, not to exceed a total dose of 3 tbsp (45 mL)

14
Q

EMESIS – HYDROGEN PEROXIDE Contradictions EDIT

A

Rodents, rabbits, birds, horses, ruminants
Contraindicated for corrosive agents and hydrocarbon ingestion.

animals with a history of cardiovascular abnormalities, poorly controlled epilepsy, or recent abdominal surgery, severely depressed, severely dehydrated, in a coma,
hyperactive, or have already vomited.

15
Q

ACTIVATED CHARCOAL use and dose

A

To adsorb (bind) ingested toxins, preventing absorption into the bloodstream
Dose- 1 to 3 g/kg body weight

16
Q

ACTIVATED CHARCOAL contradictions

A

Contraindicated in animal that ingested caustic materials. Ethanol, methanol, fertilizer, fluoride, petroleum distillates, heavy metals, iodides, nitrate, nitrites, sodium chloride, and chlorate are not effectively absorbed.

17
Q

CATHARTICS (toxins) EDIT. Speed up or slow down

A

To decrease gastrointestinal transit time
Administered with activated charcoal, or alone
Contraindicated in patients with diarrhea or
dehydration.

18
Q

ENEMAS (toxins)

A

Use plain warm or soapy water
Eliminate toxicants form the lower GI tract.
Premixed human solutions are contraindicated in small animals. Enemas are not performed in birds.

19
Q

GASTRIC LAVAGE process and contradictions (toxins)

A

Gently pump out stomach contents. Repeated until the fluid removed is clear; no more than 10 ml/kg in rabbits

Contraindicated in cases of caustic or petroleum distillate. Performed under general anesthesia with a cuffed endotracheal tube.

20
Q

ENTEROGASTRIC LAVAGE (toxins)

A

Used for lethal oral exposure
Continued until the fluid removed is clear

21
Q

The general rule of toxicology is to

A

treat the patient not the poison

22
Q

The preferred emetic agent for dogs

A

apomorphine hydrochloride

23
Q

Sedation that can result from the use of apomorphine hydrochloride for emesis can be reversed with

A

naloxone

24
Q

_____recommended in patients with hemoglobinuria.

A

Fluid diuresis

25
Q

hemoglobinuria

A

If the red blood cells break down in the blood vessels, their parts move freely in the bloodstream. If the level of hemoglobin in the blood rises too high, then hemoglobin begins to appear in the urine.

26
Q

Chelation

A

provoking the excretion of heavy metal elements from the body

27
Q

Decontamination is performed to ______
(Toxicants)

A

prevent absorption of toxicants

28
Q

Cats and acetometaphin

A

In cats, 10 mg/kg of acetaminophen has produced signs of toxicity.
Cats are deficient in the enzyme glucuronides that detoxifies acetaminophen

29
Q

Risk to humans when treating zinc poisoning

A

Following ingestion, phosphide is converted to phosphine
gas by stomach acid. Phosphine gas can cause severe respiratory distress.

Symptoms include headache or shortness of breath.

30
Q

Animals generally vomit only _____ Therefor) _____

A

40% to 60% of their stomach contents. If the toxin is not seen in the vomitus, you cannot assume that it came back up.