Topic list 3 Flashcards

1
Q

What is residual volume?

A

air remaining in the lungs after complete exhalation

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2
Q

What are the standard capacities?

A

inspiratory capacity, functional residual capacity, vital capacity, total lung capacity

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3
Q

What is functional residual capacity?

A

volume of air at the end of exhalation during normal breathing

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4
Q

What is vital capacity?

A

Total volume of exhaled air from max inspiration to max expiration

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5
Q

What is total lung capacity?

A

total volume of air in the lung at the end of max inspiration

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6
Q

What is the pressure at the base of the pleural cavity?

A

-2.5 cm H20

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7
Q

What is the pressure at the apex of the pleura cavity?

A

-10 cm H20

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8
Q

When are the lungs the smallest?

A

when transpulmonary pressure = 0

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9
Q

What is emphysema?

A

Loss of alveoli and of their elastic tissue

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10
Q

What type of system is the pulmonary circulation?

A

Low pressure / low resistance system

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11
Q

Where is the ventilation / perfusion ratio at its lowest?

A

at the bottom of the lung, where Q exceeds Va

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12
Q

What does Graham’s law state? (2)

A

rate of diffusion of a liquid is proportional to its solubility, and inversely proportional to the sqrt of its molecular weight

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13
Q

What is special about the gamma sub-unit of fetal Hb?

A

It does not bind to 2,3BPG and thus has increased affinity for O2

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14
Q

What is the O2 dissociation curve?

A

curve that illustrates the relationship bw pO2 in blood and number of O2 molecules bound to Hb

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15
Q

When is the Hgb saturation especially dependant on pO2?

A

under 60mmHg pO2

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16
Q

What is the P50 value of O2-Hb binding for a physiological adult?

A

27mmHg

17
Q

What is the Haldane effect?

A

oxygenation of blood in the lung displaces O2 from Hgb, which increases the removal of CO2 - oxygenated blood has reduced affinity for CO2

18
Q

What are the 4 types of hypoxia?

A
  • hypoxic hypoxia
  • anaemic
  • circulatory
  • histotoxic
19
Q

What is the max breathing capacity?

A

160L/min

20
Q

What is the actual pulmonary ventilation during maximal exercise?

A

110L/min

21
Q

What does Boyle’s law state?

A

the volume to which a given quantity of gas is compressed is inversely proportional to the pressure (P1V1=P2V2)

22
Q

What are the 4 things that control breathing?

A
  1. neural control centers
  2. chemoreceptors
  3. mechanoreceptors
  4. brain stem (respiratory muscles)
23
Q

What are the 3 centres of the brainstem that control breathing?

A
  • medullary center
  • apneustic center
  • pneumotaxic
24
Q

Where are mechanoreceptors found? (5)

A
  1. In the lung tissue
  2. Joints and muscles
  3. Alveolar wall
  4. Epithelial cells of the airways