Important parameters semester 1 Flashcards

1
Q

Body water content

A

0.6 x BW = 42L

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2
Q

Blood volume

A

PV / (1 - HMC) = 5L

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3
Q

Plasma volume

A

0.25 x ECF = 3.5L

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4
Q

ECF volume

A

0.2 x BW = 14L

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5
Q

ICF volume

A

0.4 x BW = 28L

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6
Q

Interstitial fluid volume

A

0.75 x ECF = 10.5L

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7
Q

Hematocrit

A

Males : 42 to 54 %

Females : 38 - 46 %

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8
Q

Hemoglobin concentration

A

12g/dL or higher

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9
Q

Blood plasma Na+ concentration

A

142mM

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10
Q

Blood plasma K+ concentration

A

4.4mM

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11
Q

Blood plasma Ca2+ concentrations

A

Total : 2.1-2.8mM

Free : 1.1-1.4mM

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12
Q

Blood plasma Cl- concentration

A

102mM

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13
Q

Blood plasma HCO3- concentration

A

2.5mM

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14
Q

Blood plasma protein concentration

A

1mM

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15
Q

Intracellular Na+ concentration

A

15mM

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16
Q

Extracellular Na+ concentration

A

135-147mM

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17
Q

Intracellular K+ concentration

A

120mM

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18
Q

Cytosolic Ca2+ concentration

A

100nM

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19
Q

Intracellular Cl- concentration

A

20mM

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20
Q

Intracellular HCO3- concentration

A

12-16mM

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21
Q

Blood plasma osmolarity and oncotic pressure

A

290mOsm/L and 28mmHg

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22
Q

Resting membrane potential of skeletal muscle cells

A

-90mV

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23
Q

Equilibrium potential of Na+ in neurons

A

+60mV

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24
Q

Equilibrium potential of K+ in neurons

A

-90mV

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25
Q

Equilibrium potential of Ca2+ in neurons

A

130mV

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26
Q

Equilibrium potential of Cl- in neurons

A

-70mV

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27
Q

Resting membrane potential of neurons

A

Around -70mV but changes depending on neuron

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28
Q

Duration of QRS coomplex of ECG

A

0.06 - 0.1s

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29
Q

Duration of P wave of ECG

A

0.08 - 0.1s

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30
Q

Duration of PQ (PR) interval

A

0.1 - 0.2s

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31
Q

Amplitude of R and T wave in ECG II lead

A

R: 0,4-1,3 mV
T: 0,1-0,6 mV

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32
Q

Stroke volume

A

EDV-ESV = 80mL

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33
Q

Amplitude of ST segment of ECG

A

supposed to be isoelectric (flat) so 0-1mV

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34
Q

Duration of cardiac cycle (HR = 75/min)

A

T = 60 / HR = 0.8 seconds (would be 1 if HR = 60)

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35
Q

Duration of systole (HR = 75/min)

A

0.27 seconds

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36
Q

Duration of diastole (HR = 75/min)

A

0.53 seconds

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37
Q

Systolic pressure in the aorta

A

120 mmHg

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38
Q

Diastolic pressure in the aorta

A

80 mmHg

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39
Q

Systolic pressure in the right ventricle

A

Less than 25 mmHg

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40
Q

Diastolic pressure in the right ventricle

A

Less than 5 mmHg

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41
Q

Systolic pressure in the left ventricle

A

About 110-120 mmHg

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42
Q

Diastolic pressure in the left ventricle

A

Low : about 5-10 mmHg

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43
Q

Systolic pressure in the pulmonary artery

A

Around 25 mmHg

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44
Q

Diastolic pressure in the pulmonary artery

A

Around 10 mmHg

45
Q

Central venous pressure (BP in the vena cavae)

A

0-5 mmHg

46
Q

Blood flow to skeletal muscle (during exercise too)

A

About 20% of the cardiac output so 1L/min, and 20L/min during max exercise

47
Q

Blood flow to splanchnic area at rest and at max exercise

A

25% of CO so 1,25L/min at rest

700mL/min at exercise

48
Q

Blood flow of heart

A

Coronary circulation is about 5% of the CO so 250mL/min

49
Q

Renal blood flow

A

1200-1300 mL/min

50
Q

Cerebrospinal fluid volume (/day, /hour, in general)

A

500mL produced / day, 25mL / hour

In general there is only 15-150mL present

51
Q

Protein concentration of CSF

A

nearly protein free

52
Q

Blood flow of brain

A

15-20% of CO so 850mL/min

53
Q

Blood flow of skin

A

2% of CO so 100mL/min

54
Q

Hydrostatic capillary pressure in arteriolar end and venular end

A

+32mmHg at arterial end

+25mmHg at venous end

55
Q

Oxygen consumption in 1 minute

A

Approximately 250mL/min

56
Q

Residual volume M and F

A

M : 1200 mL

F : 1000 mL

57
Q

Expiratory reserve volume M and F

A

M : 1200 mL

F : 800 mL

58
Q

Inspiratory reserve volume M and F

A

M : 3100 mL

F : 1900 mL

59
Q

Tidal volume

A

500mL

60
Q

Vital capacity M and F

A

M : 4800 mL

F : 3200 mL

61
Q

Total lung capacity M and F

A

M : 6000 mL

F : 4200 mL

62
Q

Functional residual capacity

A

M : 2400 mL

F : 1800 mL

63
Q

Anatomical deadspace

A

volume of gas in the conducting system : 150mL

64
Q

Alveolar deadspace

A

volume of the alveoli that is ventilated but not perfused : 0mL in physio conditions

65
Q

Physiological deadspace

A

Anatomical + alveolar = 150mL

66
Q

Alveolar ventilation

A

VA = (VCO2 * 863mmHg)/(PaCO2), around 4000mL/min

67
Q

AVDO2 in the kidney

A

15mL O2/L

68
Q

AVDO2 in the splanchnic area

A

30-40mL O2/L

69
Q

AVDO2 in the brain

A

60mL O2/L

70
Q

AVDO2 in the heart in resting condition and during exercise

A

rest: 110 ml O2/L (60-80% is extracted)

for exercise: increase = increase in blood flow, extraction already at max

71
Q

AVDO2 in the skeletal muscle in resting condition and during physical exercise

A

60mL O2/L at rest

150mL O2/L during exercise

72
Q

Conduction velocity of different type of nerves

A

A-alpha (myelinated): 80-120 m/s
A-beta (myelinated): 40-70 m/s
B: (myelinated) 5-20 m/s
C (non-myelinated): 0,5-2 m/s

73
Q

Duration of ventricular ejection (HR = 75/min)

A

0,25s

74
Q

Duration of ventricular filling (HR = 75/min)

A

0,44s

75
Q

Effective filtration pressure of capillaries in the arteriolar end and in the venular end

A

Artery : +15mmHg

Venous : -9mmHg

76
Q

AVDO2 in the systemic circulation

A

50mL 02/L

77
Q

Intrapleural pressure and alveolar pressure during inspiration

A

Intrapleural pressure= -7 to -4 mmHg

alveolar pressure= -0,7-0 mmHg

78
Q

Intrapleural pressure and alveolar pressure during expiration

A

Intrapleural pressure= -7 to -4mmHg

alveolar pressure= -0,7-0 mmHg

79
Q

Intrapleural pressure and alveolar pressure at the end of inspiration

A

Intrapleural pressure= -7 mmHg

alveolar pressure= 0 mmHg

80
Q

Intrapleural pressure and alveolar pressure at the end of expiration

A

Intrapleural pressure= -4 mmHg

alveolar pressure= 0 mmHg

81
Q

PO2 and PCO2 of the alveolar gas

A

PO2 : 100mmHg

PCO2 : 40mmHg

82
Q

PO2 and PCO2 in the arteries

A

PO2 : 95mmHg

PCO2 : 40mmHg

83
Q

PO2 and PCO2 in the veins

A

PO2 : 40mmHg

PCO2 : 46mmHg

84
Q

Concentration of O2 in the arteries

A

200ml O2/L (97% saturation)

85
Q

Concentration of O2 in the veins

A

150ml O2/L (75% saturation)

86
Q

CO2 production in resting condition

A

210mL/min

87
Q

Renal plasma flow

A

600-700mL/min

88
Q

Glomerular filtration rate

A

120mL/min

89
Q

Filtration fraction (kidney)

A

20%

90
Q

Hydrostatic pressure in AFFERENT glomerular capillaries

A

53mmHg

91
Q

Colloid osmotic pressure in AFFERENT glomerular capillaries

A

25mmHg

92
Q

Hydrostatic pressure in EFFERENT glomerular capillaries

A

51mmHg

93
Q

Colloid osmotic pressure in EFFERENT glomerular capillaries

A

33mmHg

94
Q

Hydrostatic pressure in Bowman’s space

A

12mmHg (afferent and efferent)

95
Q

Colloid osmotic pressure in Bowman’s space

A

0mmHg (afferent and efferent)

96
Q

Effective filtration pressure in the glomerular afferent and efferent capillaries

A

Afferent : 15mmHg

Efferent : 6mmHg

97
Q

Urine volume (maximal concentration)

A

0,5L/day

98
Q

Urine osmolarity (maximal concentration)

A

1200mOsm/L

99
Q

Urine volume (max dilution)

A

15-20L/day

100
Q

Urine osmolarity (max dilution)

A

30-50mOsm/L

101
Q

Osmotic concentration and pressure in the proximal tubule

A

290mOsm and 300mmHg

102
Q

Osmotic concentration and pressure in the interstitium in the cortex

A

290mOsm and 300mmHg

103
Q

Transport maximum of tubular glucose-reabsorbtion

A

375mg/min 11mM

104
Q

Buffer base

A

44-49 mEq/L

105
Q

Arterial blood pH

A

7.35-7.45

106
Q

Base excess

A

Around 0 mEq/L

107
Q

Standard HCO3-

A

24mmol/L

108
Q

Actual HCO3-

A

24mmol/L