Topic 8 Skeletal System: Bone Composition

Question 1

1. Osteoprogenitor/ osteogenic
2. Osteoblasts
3. Osteocytes
4. Osteoclasts

Answer 1

Bone has 4 types of cells surrounded by an extensive matrix:

Question 2

• Cells that are part of the mesenchymal stem cell lineage that differentiate into osteoblasts

Answer 2

1. Osteoprogenitor/ osteogenic

Question 3

• Secrete collagen and organic compounds upon which bone is formed. These cells are incapable of mitosis. As these cells release matrix materials around themselves, they become enveloped by the matrix and differentiate into osteocytes

Answer 3

2. Osteoblasts

Question 4

• Incapable of mitosis and exchange nutrients and waste material with the blood

Answer 4

3. Osteocytes

Question 5

• Resorb (destroy) bone matrix and release minerals back to the blood. These have carbonic anhydrase, and develop from WBC’s called monocytes (hematopoietic stem cells lineage)

Answer 5

4. Osteoclasts

Question 6

• osteoBlasts BUILD bone while osteoClasts CUT (breakdown) bone. Neither can carry out mitosis

Answer 6

Note