Topic 10 Immune System: Comparing B cells and T cells Flashcards
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- B cells can directly bind intact antigens at their receptor sites, but T cells must have the antigen presented as fragments from other cells
- Both T cells (developing in thymus) and B cells (develop in bone marrow) undergo negative selection, as if they bind to self-cells too tightly, they are eliminated. T cells also undergo positive selection, which ensures T cells can recognize self-cells to some extent
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