Topic 10 Immune System: Responses of Acquired/Adaptive Immune System

Question 1

• Effective against infected cells, uses mostly T cells and responds to any non-self cells, including cells invaded by pathogen. When the non-self cell binds to a T cell, clonal selection occurs, as well as the following chain of events
  a. Produce cytotoxic T cells and helper T cells
  b. Helper T cells bind macrophages, and macrophages engulf pathogens
  c. Helper T cells produce interleukins to stimulate proliferation of T cells, B cells, and macrophages

Answer 1

1. Cell-mediated Response

Question 2

• Responds to antigens or pathogens that circulate in lymph or blood (such as bacteria, fungi, parasites, viruses, or blood toxins). The following events occur:
  a. Macrophage and helper T cells stimulate B cell production
  b. B cells produce plasma cells
  c. B cells produce memory cells
  d. General progression of B cells: naïve -> mature -> plasma -> antibody
  e. Note that antibodies are released from plasma cells, are specific for an antigen, and a single B-lymphocyte produces only one antibody type

Answer 2

2. Humoral Response (antibody mediated response)