Thyroid Disorders Flashcards
True or false: Thyroid disorders are more prominent in men than women
False. More prominent in women
Normal TSH range
0.5 - 4.7 mlU/L
Parameters of TSH in hypothyroidism
TSH > 4.7
Parameters of TSH in hyperthyroidism
TSH < 0.5
True or false: No antithyroid drug is useful in treating thyroiditis
True
Excess ingestion of what can interfere with immunoassays leading to falsely elevated TT4, FT4 and TT3, and falsely low TSH levels?
Biotin
What is Plummer’s disease and the first line treatment?
Hyperthyroidism characterized by multinodular goiters. Surgery is treatment of choice
Thyroid storm is often seen in what form of hyperthyroidism?
Graves’ Disease
What are the two main goals of hyperthyroidism treatment?
- Relieve signs and symptoms
- Become euthyroid
What is the Wolff-Chaikoff effect?
Transient inhibition of thyroid hormone biosynthesis following the administration of iodides
Which two beta blockers partially block peripheral conversion of T4 to T3?
.Propranolol
.Nadolol
Which is the preferred beta blocker in thyroid storm?
IV esmolol
What is the most common cause of spontaneous hypothyroidism?
Hashimoto’s disease
What is the term for acute decompensated hypothyroidism?
Myxedema coma
Elevated TSH with normal FT4 is a sign of what?
Subclinical hypothyroidism
Replacement dose of levothyroxine
1.6 mcg/kg/day (IBW)
Levothyroxine starting dose in relatively healthy elderly patients
50 mcg/day
Levothyroxine starting dose in patients with known CAD
12.5-25 mcg/day
True or false: Amiodarone can block conversion of T4->T3
True
Liotrix contains T4 and T3 in what ratio?
4:1
What dose increase in suggested pregnancy?
~50% increase
