BPH

Question 1

Collective terms for symptoms associated with BPH

Answer 1

LUTS - lower urinary tract symptoms

Question 2

Examples of obstructive symptoms

Answer 2

.Hesitancy
.Difficulty initiating stream/weak stream
.Straining
.Incomplete emptying
.Dribbling

Question 3

Examples of storage symptoms

Answer 3

.Frequency
.Nocturia
.Urgency
.Incontinence
.Dysuria

Question 4

Why are non-selective alpha blockers generally avoided in BPH treatment?

Answer 4

Hypotensive effect

Question 5

True or false: ED is more prevalent with non-selective alpha blockers

Answer 5

False. More prevalent with selective alpha blockers

Question 6

Which is the only PDE5 inhibitor FDA approved for LUTS?

Answer 6

Tadalafil

Question 7

Which class of medications is first line treatment if chief comlaints are both BPH and ED?

Answer 7

PDE5 inhibitors

Question 8

5 alpha reductase inhibitors MOA

Answer 8

Block the conversion of testosterone to DHT, shrinking the prostate (~25%) and reducing further growth

Question 9

Finasteride blocks (Type I /Type II / both) and reduces DHT (70-90% / to near zero)

Answer 9

Type II. 70-90%

Question 10

Dutasteride blocks (Type I /Type II / both) and reduces DHT (70-90% / to near zero)

Answer 10

Both. To near zero

Question 11

Antimuscarinic agents are contraindicated in which condition?

Answer 11

Narrow-angle glaucoma