Schizophrenia Flashcards
1
Q
Which of the following is considered a positive symptom of disorganization?
a. Flat affect
b. Lack of interest
c. Disorganization
d. Poverty of speech
A
c. Disorganization
2
Q
First line agents for schizophrenia?
A
Second gen antipsychotics
3
Q
True or false: Second gen antipsychotics have high D2 and high serotonin antagonist activity
A
False. Low D2 antagonism
4
Q
Droperidol BBW
A
QTc prolongation
5
Q
First line 2nd gen antipsychotics for treatment naive patients
A
Aripiprazole, risperidone, ziprasidone
6
Q
Main goal of antipsychotic maintenance therapy
A
Avoid relapse
7
Q
3 main MOAs of 2nd gen antipsychotics
A
.Antagonists of dopamine and serotonin receptors
.D2 antagonism with rapid dissociation
.D2 partial agonism
8
Q
Risperidone MOA
A
Potent D2 and 5-HT2 antagonist
