THROMBOGENESIS Flashcards

1
Q

irreversibly inhibits cyclooxygenase inhibiting TXA2 synthesis

A

aspirin

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2
Q

inhibits ADP induced expression of GpIIb/IIIa by irreversibly blocking P2Y12 receptor

A

clopidogrel, prausgrel, ticlopidine

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3
Q

inhibits GpIIb/IIIa directly

A

abciximab
eptifibatide
tirofiban

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4
Q

activates vWF to bind GpIb

failure of aggregation with ristocetin assay occurs in von Willebrand diseases and Bernard soulier syndrome

A

ristocetin

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5
Q

carries/protects factor VIII

A

vWF

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