THROMBOGENESIS Flashcards
1
Q
irreversibly inhibits cyclooxygenase inhibiting TXA2 synthesis
A
aspirin
2
Q
inhibits ADP induced expression of GpIIb/IIIa by irreversibly blocking P2Y12 receptor
A
clopidogrel, prausgrel, ticlopidine
3
Q
inhibits GpIIb/IIIa directly
A
abciximab
eptifibatide
tirofiban
4
Q
activates vWF to bind GpIb
failure of aggregation with ristocetin assay occurs in von Willebrand diseases and Bernard soulier syndrome
A
ristocetin
5
Q
carries/protects factor VIII
A
vWF