CLASSIC/RELEVANT TX II

Question 1

Trichomonas vaginalis

Answer 1

Metronidazole (patient and partner)

Question 2

Streptococcus pyogenes

Answer 2

Penicillin prophylaxis

Question 3

Streptococcus pneumoniae

Answer 3

Penicillin/cephalosporin (systemic infection, pneumonia),

vancomycin (meningitis)

Question 4

Staphylococcus aureus

Answer 4

MSSA: nafcillin, oxacillin, dicloxacillin (antistaphylococcal penicillins); MRSA: vancomycin,
daptomycin, linezolid, ceftaroline

Question 5

Enterococci

Answer 5

Vancomycin, aminopenicillins/cephalosporins

Question 6

Rickettsia rickettsii

Answer 6

Doxycycline, chloramphenicol

Question 7

Clostridium difficile

Answer 7

Oral metronidazole; if refractory, oral vancomycin

Question 8

Mycobacterium tuberculosis

Answer 8

RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)

Question 9

UTI prophylaxis

Answer 9

TMP-SMX

Question 10

Influenza

Answer 10

Oseltamivir, zanamivir

Question 11

CMV

Answer 11

Ganciclovir, foscarnet, cidofovir

Question 12

Patent ductus arteriosus

Answer 12

Close with indomethacin; keep open with PGE analogs

Question 13

Stable angina

Answer 13

Sublingual nitroglycerin

Question 14

Buerger disease

Answer 14

Smoking cessation

Question 15

Kawasaki disease

Answer 15

IVIG, aspirin

Question 16

Temporal arteritis

Answer 16

High-dose steroids

Question 17

Granulomatosis with polyangiitis (Wegener)

Answer 17

Cyclophosphamide, corticosteroids

Question 18

Hypercholesterolemia

Answer 18

Statin (first-line)

Question 19

Hypertriglyceridemia

Answer 19

Fibrate

Question 20

Arrhythmia in damaged cardiac tissue

Answer 20

Class IB antiarrhythmic (lidocaine, mexiletine)

Question 21

Prolactinoma

Answer 21

Cabergoline/bromocriptine (dopamine agonists)

Question 22

Diabetes insipidus

Answer 22

Desmopressin (central); hydrochlorothiazide,

indomethacin, amiloride (nephrogenic)

Question 23

SIADH

Answer 23

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

Question 24

Diabetic ketoacidosis

Answer 24

Fluids, insulin, K+

Question 25

Diabetes mellitus type 1

Answer 25

Dietary intervention (low carbohydrate) + insulin
replacement

Question 26

Diabetes mellitus type 2

Answer 26

Dietary intervention, oral hypoglycemics, and insulin (if

refractory)

Question 27

Pheochromocytoma

Answer 27

α-antagonists (eg, phenoxybenzamine)

Question 28

Carcinoid syndrome

Answer 28

Octreotide

Question 29

Crohn disease

Answer 29

Corticosteroids, infliximab, azathioprine

Question 30

Ulcerative colitis

Answer 30

5-ASA preparations (eg, mesalamine), 6-mercaptopurine, infliximab, colectomy

Question 31

Sickle cell disease

Answer 31

Hydroxyurea ( fetal hemoglobin)