CLASSIC/RELEVANT TX

Question 1

Ethylene glycol/methanol intoxication

Answer 1

Fomepizole (alcohol dehydrogenase inhibitor)

Question 2

Chronic hepatitis B or C

Answer 2

IFN-α (HBV and HCV); ribavirin, simeprevir, sofosbuvir (HCV)

Question 3

Streptococcus bovis

Answer 3

Penicillin prophylaxis; evaluation for colon cancer if

linked to endocarditis

Question 4

Clostridium botulinum

Answer 4

Antitoxin

Question 5

Clostridium tetani

Answer 5

Antitoxin

Question 6

Haemophilus influenzae (B)

Answer 6

Amoxicillin ± clavulanate (mucosal infections),

ceftriaxone (meningitis), rifampin (prophylaxis)

Question 7

Neisseria gonorrhoeae

Answer 7

Ceftriaxone (add doxycycline to cover likely concurrent

C trachomatis)

Question 8

Neisseria meningitidis

Answer 8

Penicillin/ceftriaxone, rifampin (prophylaxis)

Question 9

Legionella pneumophila

Answer 9

Macrolides (eg, azithromycin)

Question 10

Pseudomonas aeruginosa

Answer 10

Piperacillin/tazobactam, aminoglycosides, carbapenems

Question 11

Treponema pallidum

Answer 11

Penicillin G

Question 12

Chlamydia trachomatis

Answer 12

Doxycycline (+ ceftriaxone for gonorrhea coinfection),
oral erythromycin to treat chlamydial conjunctivitis in
infants

Question 13

Candida albicans

Answer 13

Topical azoles (vaginitis); nystatin, fluconazole,
caspofungin (oral/esophageal); fluconazole, caspofungin, amphotericin B (systemic)

Question 14

Cryptococcus neoformans

Answer 14

Induction with amphotericin B and flucytosine, maintenance with fluconazole (in AIDS patients)

Question 15

Sporothrix schenckii

Answer 15

Itraconazole, oral potassium iodide

Question 16

Pneumocystis jirovecii

Answer 16

TMP-SMX (prophylaxis and treatment in immunosuppressed patients, CD4 < 200/mm3)

Question 17

Toxoplasma gondii

Answer 17

Sulfadiazine + pyrimethamine

Question 18

Malaria

Answer 18

Chloroquine, mefloquine, atovaquone/proguanil (for

blood schizont), primaquine (for liver hypnozoite)